Elderly women with oral exostoses had higher bone mineral density

被引:0
作者
Takayuki Hosoi
Tomohisa Yoda
Masatsune Yamaguchi
Hitoshi Amano
Hajime Orimo
机构
[1]  Endocrinology Section,
[2] Tokyo Metropolitan Geriatric Center,undefined
[3] 35-2 Sakaechou,undefined
[4] Itabashi-ku,undefined
[5] Tokyo 173-0015 Japan,undefined
[6]  Department of Dentistry and Oral Surgery,undefined
[7] Tokyo Metropolitan Geriatric Center,undefined
[8] Tokyo,undefined
[9] Japan,undefined
[10]  Department of Pharmacology,undefined
[11] School of Dentistry,undefined
[12] Showa University,undefined
[13] Tokyo,undefined
[14] Japan,undefined
来源
Journal of Bone and Mineral Metabolism | 2003年 / 21卷
关键词
Key words osteoporosis; bone mineral density; oral exostosis; torus palatinus; LRP5;
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摘要
 We examined the relationship between two opposite phenomena in elderly bone, bone loss (osteoporosis) and excessive bone formation (oral exostosis). We recruited, randomly, 44 female subjects without any conditions known to affect bone metabolism. The subjects were examined for exostosis, and bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry. The Z score of the BMD was calculated; this is the deviation from the weight-adjusted average BMD of each age. Subjects with palatal tori (n = 15) had a higher femoral BMD than controls (n = 14) (0.580 ± 0.213 vs −0.271 ± 0.182; P = 0.0054). The subjects with palatal tori (n = 12) also had a higher BMD than controls (n = 12) at the radius (0.417 ± 0.235 vs −0.533 ± 0.294; P = 0.0194). In addition, subjects with mandibular tori (n = 13) had a higher femoral BMD than controls (n = 14) (0.569 ± 0.242 vs −0.271 ± 0.182; P = 0.0097). These results suggest that some common mechanisms are involved in the elevation of skeletal BMD and the occurrence of oral exostoses.
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页码:120 / 122
页数:2
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