A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study)

被引：0

作者：

Takekazu Iwata

Ichiro Yoshino

Shigetoshi Yoshida

Norihiko Ikeda

Masahiro Tsuboi

Yuji Asato

Nobuyuki Katakami

Kazuhiro Sakamoto

Yoshinori Yamashita

Jiro Okami

Tetsuya Mitsudomi

Motohiro Yamashita

Hiroshi Yokouchi

Kenichi Okubo

Morihito Okada

Mitsuhiro Takenoyama

Masayuki Chida

Keisuke Tomii

Motoki Matsuura

Arata Azuma

Tae Iwasawa

Kazuyoshi Kuwano

Shuji Sakai

Kenzo Hiroshima

Junya Fukuoka

Kenichi Yoshimura

Hirohito Tada

Kazuhiko Nakagawa

Yoichi Nakanishi

机构：

[1] Chiba University Graduate School of Medicine,Department of General Thoracic Surgery

[2] Tokyo Medical University Hospital,First Department of Surgery

[3] National Cancer Center Hospital East,Department of Thoracic Surgery

[4] Ibaraki Prefectural Central Hospital,Department of Thoracic Surgery

[5] Institute of Biomedical Research and Innovation,Division of Integrated Oncology

[6] National Hospital Organization Yokohama Medical Center,Department of Respiratory Surgery

[7] National Hospital Organization,Department of Respiratory Surgery

[8] Kure Medical Center and Chugoku Cancer Center,Department of General Thoracic Surgery

[9] Osaka Medical Center for Cancer and Cardiovascular Diseases,Division of Thoracic Surgery, Department of Surgery

[10] Kinki University Faculty of Medicine,Department of Thoracic Surgery

[11] Shikoku Cancer Center,Department of Pulmonary Medicine

[12] Fukushima Medical University,Department of Thoracic Surgery

[13] Tokyo Medical and Dental University,Department of Surgical Oncology

[14] Hiroshima University,Department of Thoracic Oncology

[15] National Kyushu Cancer Center,Department of General Thoracic Surgery

[16] Dokkyo Medical University,Department of Respiratory Medicine

[17] Kobe City Medical Center General Hospital,Department of Thoracic Surgery

[18] Hiroshima City Hospital,Department of Pulmonary Medicine and Oncology

[19] Graduate School of Medicine,Department of Radiology

[20] Nippon Medical School,Department of Internal Medicine, Division of Respiratory Medicine

[21] Kanagawa Cardiovascular and Respiratory Center,Department of Diagnostic Imaging and Nuclear Medicine

[22] Jikei University School of Medicine,Department of Pathology

[23] Tokyo Women’s Medical University,Department of Pathology

[24] Tokyo Women’s Medical University Yachiyo Medical Center,Department of Thoracic Surgery

[25] Nagasaki University Graduate School of Biomedical Sciences,Department of Medical Oncology

[26] Innovative Clinical Research Center,Research Institute for Diseases of the Chest

[27] Kanazawa University Hospital,undefined

[28] Suita Tokushukai Hospital,undefined

[29] Kinki University School of Medicine,undefined

[30] Graduate School of Medical Sciences,undefined

[31] Kyushu University,undefined

来源：

Respiratory Research | / 17卷

关键词：

Idiopathic pulmonary fibrosis; Acute exacerbation; Lung cancer; Surgery; Pirfenidone;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 168 条

[1]

Hubbard R(2000)Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study Am J Respir Crit Care Med 161 5-8

[2]

Venn A(2007)Acute exacerbation of idiopathic pulmonary fibrosis Chest 132 1652-8

[3]

Lewis S(2004)Perioperative lung injury: acute exacerbation of idiopathic pulmonary fibrosis and acute interstitial pneumonia after pulmonary resection Nihon Geka Gakkai Zasshi 105 757-62

[4]

Britton J(2003)Pulmonary fibrosis and lung cancer: risk and benefit analysis of pulmonary resection J Thorac Cardiovasc Surg 125 1321-7

[5]

Hyzy R(2015)Thoracic and cardiovascular surgery in Japan during 2013 Gen Thorac Cardiovasc Surg 63 670-701

[6]

Huang S(2012)The importance of intraoperative fluid balance for the prevention of postoperative acute exacerbation of idiopathic pulmonary fibrosis after pulmonary resection for primary lung cancer Eur J Cardiothorac Surg 41 e161-5

[7]

Myers J(2011)Safety of postoperative administration of human urinary trypsin inhibitor in lung cancer patients with idiopathic pulmonary fibrosis PLoS One 6 e29053-54

[8]

Flaherty K(2014)Prophylaxis for acute exacerbation of interstitial pneumonia after lung resection Asian Cardiovasc Thorac Ann 8 948-11

[9]

Martinez F(2014)Impact and predictors of acute exacerbation of interstitial lung diseases after pulmonary resection for lung cancer J Thorac Cardiovasc Surg 147 1604-73

[10]

Hoshikawa Y(1999)Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis J Pharmacol Exp Ther 291 367-92

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