CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis

被引：0
作者：
A. L. Goodman
C. D. Murray
J. Watkins
P. D. Griffiths
D. P. Webster
机构：
[1] University College London,Department of Infection and Immunity
[2] University College London Medical School,Centre for Virology
[3] Royal Free London NHS Foundation Trust,Department of Gastroenterology
[4] Royal Free London NHS Foundation Trust,Department of Cellular Pathology
来源：
European Journal of Clinical Microbiology & Infectious Diseases | 2015年 / 34卷
关键词：
Human Immunodeficiency Virus; Inflammatory Bowel Disease; Immunocompetent Patient; Immunocompetent Host; Severe Colitis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test. There is controversy in the literature as to the significance of the detection of CMV in the gut. Whilst the importance of CMV and reactivation of the virus is clear in those patients such as allograft recipients with established immune compromise, the role is less clear in patients with less damaged immune systems. We explore whether the detection of CMV in such cases influences outcome and how it should be optimally managed. We discuss the optimal management of such cases, according to current guidelines, with a review of the literature.
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页码：13 / 18
页数：5
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