Family-based study of brain-derived neurotrophic factor (BDNF) gene polymorphism in alcohol dependence

被引：0
作者：
Anna Grzywacz
Agnieszka Samochowiec
Andrzej Ciechanowicz
Jerzy Samochowiec
机构：
[1] Pomeranian Medical University,Department of Psychiatry
[2] University of Szczecin,Interdepartmental Unit for Pedagogical Education
[3] Pomeranian Medical University,Department of Laboratory Diagnostics and Molecular Medicine
来源：
Pharmacological Reports | 2010年 / 62卷
关键词：
gene; alcohol dependence; TDT (transmission disequilibrium test); trios; family;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Brain-derived neurotrophic factor (BDNF) belongs to a family of proteins related to the nerve growth factor family, which are responsible for the proliferation, survival and differentiation of neurons. BDNF is thought to be involved in the pathogenesis of bipolar disorder, schizophrenia, eating disorders and addiction. We hypothesize that a functionally relevant polymorphism of the BDNF gene promoter may be associated with the pathogenesis of alcohol dependence.
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页码：938 / 941
页数：3
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