Cardiac Fibroblast Activation Induced by Oxygen–Glucose Deprivation Depends on the HIF-1α/miR-212-5p/KLF4 Pathway

被引：0
|
作者：
Hongbing Li
Chenxing Li
Tao Zheng
Yaning Wang
Jin Wang
Xiaojuan Fan
Xueyang Zheng
Gang Tian
Zuyi Yuan
Tao Chen
机构：
[1] First Affiliated Hospital of Xi’an Jiaotong University,Department of Cardiology
[2] Navy Medical University,Department of Organ Transplantation, Shanghai Changzheng Hospital
来源：
Journal of Cardiovascular Translational Research | 2023年 / 16卷
关键词：
HIF-1α; miR-212-5p; OGD; KLF4; Cardiac fibroblasts; Myocardial fibrosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：778 / 792
页数：14
相关论文
共 50 条
  • [31] Dexmedetomidine attenuates oxygen-glucose deprivation/reperfusion-induced inflammation through the miR-17-5p/TLR4/NE-κB axis
    Suo, Liangyuan
    Wang, Mingyu
    BMC ANESTHESIOLOGY, 2022, 22 (01)
  • [32] Dexmedetomidine attenuates oxygen-glucose deprivation/ reperfusion-induced inflammation through the miR-17-5p/ TLR4/ NF-κB axis
    Liangyuan Suo
    Mingyu Wang
    BMC Anesthesiology, 22
  • [33] Troxerutin attenuates oxygen-glucose deprivation and reoxygenation-induced oxidative stress and inflammation by enhancing the PI3K/AKT/HIF-1α signaling pathway in H9C2 cardiomyocytes
    Yu, Zhang-Ping
    Yu, Han-Qiao
    Li, Jun
    Li, Chao
    Hua, Xian
    Sheng, Xiao-Sheng
    MOLECULAR MEDICINE REPORTS, 2020, 22 (02) : 1351 - 1361
  • [34] Circvrk1 downregulation attenuates brain microvascular endothelial cell damage induced by oxygen–glucose deprivation through modulating the miR-150-5p/MLLT1 axis
    Lina Tan
    Lingjun Wang
    Jiajun Liu
    Yue Yu
    Experimental Brain Research, 2023, 241 : 781 - 791
  • [35] MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen-glucose deprivation/reoxygenation
    Deng, Yuan
    Wang, Ganlan
    Hou, Dan
    Zhang, Lei
    Pei, Chaoying
    Yang, Guoshuai
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2025, 61 (02) : 178 - 188
  • [36] HIF-1α-activated long non-coding RNA KDM4A-AS1 promotes hepatocellular carcinoma progression via the miR-411-5p/KPNA2/AKT pathway
    Chen, Tianxiang
    Liu, Runkun
    Niu, Yongshen
    Mo, Huanye
    Wang, Hao
    Lu, Ye
    Wang, Liang
    Sun, Liankang
    Wang, Yufeng
    Tu, Kangsheng
    Liu, Qingguang
    CELL DEATH & DISEASE, 2021, 12 (12)
  • [37] HIF-1α-activated long non-coding RNA KDM4A-AS1 promotes hepatocellular carcinoma progression via the miR-411-5p/KPNA2/AKT pathway
    Tianxiang Chen
    Runkun Liu
    Yongshen Niu
    Huanye Mo
    Hao Wang
    Ye Lu
    Liang Wang
    Liankang Sun
    Yufeng Wang
    Kangsheng Tu
    Qingguang Liu
    Cell Death & Disease, 12
  • [38] LncRNA MIAT knockdown alleviates oxygen-glucose deprivation-induced cardiomyocyte injury by regulating JAK2/STAT3 pathway via miR-181a-5p
    Tan, Jian-Kai
    Ma, Xiao-Feng
    Wang, Guang-Neng
    Jiang, Chang-Rong
    Gong, Hui-Qin
    Liu, Huan
    JOURNAL OF CARDIOLOGY, 2021, 78 (06) : 586 - 597
  • [39] LncRNA DANCR attenuates brain microvascular endothelial cell damage induced by oxygen-glucose deprivation through regulating of miR-33a-5p/XBP1s
    Zhang, Mengqi
    Tang, Mimi
    Wu, Qian
    Wang, Zhuolu
    Chen, Zhuohui
    Ding, Hui
    Hu, Xinhang
    Lv, Xinyi
    Zhao, Songfeng
    Sun, Jingyan
    Kang, Shuntong
    Wu, Tong
    Xiao, Bo
    AGING-US, 2020, 12 (02): : 1759 - 1772
  • [40] Circulating miR-574-5p shows diagnostic and prognostic significance and regulates oxygen-glucose deprivation (OGD)-induced inflammatory activation of microglia by targeting ATP2B2
    Yin, Xia
    Zhang, Chunlei
    MOLECULAR AND CELLULAR PROBES, 2025, 79
12345