Cardiac Fibroblast Activation Induced by Oxygen–Glucose Deprivation Depends on the HIF-1α/miR-212-5p/KLF4 Pathway

被引：0
|
作者：
Hongbing Li
Chenxing Li
Tao Zheng
Yaning Wang
Jin Wang
Xiaojuan Fan
Xueyang Zheng
Gang Tian
Zuyi Yuan
Tao Chen
机构：
[1] First Affiliated Hospital of Xi’an Jiaotong University,Department of Cardiology
[2] Navy Medical University,Department of Organ Transplantation, Shanghai Changzheng Hospital
来源：
Journal of Cardiovascular Translational Research | 2023年 / 16卷
关键词：
HIF-1α; miR-212-5p; OGD; KLF4; Cardiac fibroblasts; Myocardial fibrosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：778 / 792
页数：14
相关论文
共 50 条
  • [1] Cardiac Fibroblast Activation Induced by Oxygen-Glucose Deprivation Depends on the HIF-1α/miR-212-5p/KLF4 Pathway
    Li, Hongbing
    Li, Chenxing
    Zheng, Tao
    Wang, Yaning
    Wang, Jin
    Fan, Xiaojuan
    Zheng, Xueyang
    Tian, Gang
    Yuan, Zuyi
    Chen, Tao
    JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2023, 16 (04) : 778 - 792
  • [2] Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway
    Zhao, Kun
    Jiang, Yaping
    Zhang, Jing
    Shi, Jing
    Zheng, Pengxiang
    Yang, Chuanxi
    Chen, Yihui
    CELL CYCLE, 2022, 21 (19) : 2091 - 2108
  • [3] 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) alleviates lung injury by inhibiting SIRT6-HIF-1α signaling pathway activation through the upregulation of miR-212-5p expression
    Ai, Li
    Li, Ran
    Cao, Yu
    Liu, Zhijuan
    Niu, Xiaoqun
    Li, Yongxia
    MOLECULAR BIOLOGY REPORTS, 2024, 51 (01)
  • [4] Apigenin suppresses TGF-β1-induced cardiac fibroblast differentiation and collagen synthesis through the downregulation of HIF-1α expression by miR-122-5p
    Wang Feng
    Zhao Ying
    Fan Ke
    Xie Mei-Lin
    PHYTOMEDICINE, 2021, 83
  • [5] Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway
    Shyanne Page
    Snehal Raut
    Abraham Al-Ahmad
    NeuroMolecular Medicine, 2019, 21 : 414 - 431
  • [6] Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood-Brain Barrier is Partially Mediated Through the HIF-1 Pathway
    Page, Shyanne
    Raut, Snehal
    Al-Ahmad, Abraham
    NEUROMOLECULAR MEDICINE, 2019, 21 (04) : 414 - 431
  • [7] Blockage of miR-485-5p on Cortical Neuronal Apoptosis Induced by Oxygen and Glucose Deprivation/Reoxygenation Through Inactivating MAPK Pathway
    Jiangliu Yin
    Huan Chen
    Suonan Li
    Shuai Zhang
    Xieli Guo
    NeuroMolecular Medicine, 2021, 23 : 256 - 266
  • [8] Blockage of miR-485-5p on Cortical Neuronal Apoptosis Induced by Oxygen and Glucose Deprivation/Reoxygenation Through Inactivating MAPK Pathway
    Yin, Jiangliu
    Chen, Huan
    Li, Suonan
    Zhang, Shuai
    Guo, Xieli
    NEUROMOLECULAR MEDICINE, 2021, 23 (02) : 256 - 266
  • [9] JMJD5 attenuates oxygen-glucose deprivation and reperfusion-induced injury in cardiomyocytes through regulation of HIF-1α-BNIP3
    Zhang, Ya-Nan
    Pang, Ya-Xiang
    Liu, Da-Wei
    Hu, Hai-Juan
    Xie, Rui-Qin
    Cui, Wei
    KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2022, 38 (01): : 38 - 48
  • [10] miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway
    Zhou, Zhongquan
    Chen, Songwen
    Tian, Zhiming
    Deng, Shibing
    Yi, Xuying
    Yang, Shaning
    Yang, Xuexin
    Jin, Lijun
    Shi, Wanqing
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 52 (09) : 927 - 934
12345