Nutrition and Dry Eye

被引:0
作者
Aragona P. [1 ]
Rania L. [1 ]
Micali A. [2 ]
Puzzolo D. [2 ]
机构
[1] Ocular Surface Diseases Unit, Department of Experimental Medical-Surgical Sciences, University of Messina, Policlinico Universitario, Via Consolare Valeria 1, Messina
[2] Department of Biomedical Sciences and Morphofunctional Imaging, University of Messina, Policlinico Universitario, Via Consolare Valeria 1, Messina
关键词
Amino acids; Conjunctival epithelium; Corneal epithelium; Diabetes; Dry eye; Neuroprotectins; Nutrition; Ocular surface; Omega-3; Omega-6; Resolvins; Sjögren’s syndrome; Vitamins;
D O I
10.1007/s40135-013-0011-7
中图分类号
学科分类号
摘要
The tear film is a complex mixture of molecules such as lipids, mucins and water, whose function is to protect the eye from external factors such as environmental stimuli, traumas and infections. It is secreted by specific structures, but also, in part, derives from the blood stream. Substances taken with food can directly or indirectly influence tear film composition so inducing changes of the ocular surface. When the tear film is altered a condition known as dry eye may develop. Diet derived substances can be of help in the treatment of this condition. Among these substances essential fatty acids, of the omega-6 and 3 series, can play a role in the control of inflammation and in promoting the recovery of the ocular surface structures. Also some aminoacid implementation, with molecules that participate to collage composition, may participate in the recovery of the ocular surface structures undergoing the inflammatory stress. © 2013, Springer Science + Business Media New York.
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页码:58 / 64
页数:6
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共 54 条
  • [1] Gipson I.K., The ocular surface: the challenge to enable and protect vision: the Friedenwald lecture, Invest Ophthalmol Vis Sci, 48, pp. 4391-4398, (2007)
  • [2] Green-Church K.B., Butovich I., Willcox M., Et al., The international workshop on meibomian gland dysfunction: Report of the subcommittee on tear film lipids and lipid-protein interactions in health and disease, Invest Ophthalmol Vis Sci, 52, pp. 1979-1993, (2011)
  • [3] Caffery B.E., Influence of diet on tear function, Optom Vis Sci, 68, pp. 58-72, (1991)
  • [4] Guzman-Aranguez A., Argueso P., Structure and biological roles of mucin-type O-glycans at the ocular surface, Ocul Surf, 8, pp. 8-17, (2010)
  • [5] Micali A., Puzzolo D., Pisani A., Et al., Ultrastructural study of the conjunctival epithelium in the Mongolian gerbil (Meriones unguiculatus), Ophthalmic Res, 30, pp. 244-254, (1998)
  • [6] The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007), Ocul Surf, 5, pp. 75-92, (2007)
  • [7] Dao A.H., Spindle J.D., Harp B.A., Et al., Association of dyslipidemia in moderate to severe meibomian gland dysfunction, Am J Ophthalmol, 150, pp. 371-375, (2010)
  • [8] Aragona P., Giuffrida S., Di Stefano G., Et al., Ocular surface changes in type 1 diabetic patients, Adv Exp Med Biol, 506, pp. 667-672, (2002)
  • [9] Khandait D.W., Vasudeo N.D., Zodpey S.P., Et al., Vitamin A intake and xerophthalmia among Indian children, Public Health, 113, pp. 69-72, (1999)
  • [10] Eckert M.J., Perry J.T., Sohn V.Y., Et al., Incidence of low vitamin A levels and ocular symptoms after Roux-en-Y gastric bypass, Surg Obes Relat Dis, 6, pp. 653-657, (2010)