Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways

Sniekers YH(2008)Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment - a systematic approach Osteoarthr Cartil 16 533-541

Weinans H(2014)The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis Mediators Inflamm 2014 561459-439

Bierma-Zeinstra SM(2018)Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes Biomed Pharmacother 107 433-170

van Leeuwen JP(2016)Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes Biomol Ther (Seoul) 24 163-313

van Osch GJ(2007)Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis Curr Drug Targets 8 305-1912

Wojdasiewicz P(2020)The Role of Inflammation in the Pathogenesis of Osteoarthritis Mediators Inflamm 2020 8293921-523

Poniatowski ŁA(2002)Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298 1911-640

Szukiewicz D(2015)NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review Front Mol Neurosci 8 77-150

Huang X(2019)Systemic drugs with impact on osteoarthritis Drug Metab Rev 51 498-413

Xi Y(2021)Role of intracellular signaling pathways and their inhibitors in the treatment of inflammation Inflammopharmacology 29 617-54

Sniekers YH(2008)Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment - a systematic approach Osteoarthr Cartil 16 533-541

Weinans H(2014)The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis Mediators Inflamm 2014 561459-439

Bierma-Zeinstra SM(2018)Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes Biomed Pharmacother 107 433-170

van Leeuwen JP(2016)Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes Biomol Ther (Seoul) 24 163-313

van Osch GJ(2007)Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis Curr Drug Targets 8 305-1912

Wojdasiewicz P(2020)The Role of Inflammation in the Pathogenesis of Osteoarthritis Mediators Inflamm 2020 8293921-523

Poniatowski ŁA(2002)Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298 1911-640

Szukiewicz D(2015)NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review Front Mol Neurosci 8 77-150

Huang X(2019)Systemic drugs with impact on osteoarthritis Drug Metab Rev 51 498-413

Xi Y(2021)Role of intracellular signaling pathways and their inhibitors in the treatment of inflammation Inflammopharmacology 29 617-54