Astaxanthin production by Phaffia rhodozymaenhanced in fed-batch culture with glucose and ethanol feeding

被引:0
作者
Y. Yamane
K. Higashida
Y. Nakashimada
T. Kakizono
N. Nishio
机构
[1] Hiroshima University,Department of Fermentation Technology, Faculty of Engineering
来源
Biotechnology Letters | 1997年 / 19卷
关键词
Glucose; Organic Chemistry; Carbon Source; Cell Mass; High Cell;
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学科分类号
摘要
Of various carbon sources, examined for the cultivation of Phaffia rhodozyma, ethanol enhanced the astaxanthin content but severely decreased growth. Therefore, high cell mass was obtained by glucose fed-batch culture with pH-stat, and the ethanol feeding was performed based on DO-stat. As a result of this two-stage fed-batch cultivation, 30 g dry cells per liter were obtained, and the astaxanthin content reached 0.72 mg/g, which was 2.2-fold higher than that without ethanol feeding.
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页码:1109 / 1111
页数:2
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