The Role of Stem and Pluripotent Cells in Differentiation and the Neoplastic Transformation of Pancreatic Cells

被引：0
|
作者：
L. E. Gurevich
I. A. Kazantseva
E. V. Borodataya
机构：
[1] Vladimirskii Moscow Regional Clinical Institute (MONIKI),Institute of Human Morphology
[2] Russian Academy of Medical Sciences,undefined
来源：
Biology Bulletin of the Russian Academy of Sciences | 2001年 / 28卷
关键词：
Embryonic Development; Pancreatic Tumor; Tumor Differentiation; Favorable Prognosis; Embryonic Cell;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Certain differentiation-specific antigenic determinants are characteristic of pancreatic cells at each stage of embryonic development. Using immunohistochemical markers, we have demonstrated that the cells of several pancreatic tumors express some fetal proteins characteristic of embryonic cells of the pancreas. We propose that the presence of fetal antigens and proteins in the tumor is a sign of a lower tumor differentiation and a less favorable prognosis.
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页码：636 / 641
页数：5
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