Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease

被引：0

作者：

Johannes Holle

Uwe Querfeld

Marietta Kirchner

Alexandros Anninos

Jürgen Okun

Daniela Thurn-Valsassina

Aysun Bayazit

Ana Niemirska

Nur Canpolat

Ipek Kaplan Bulut

Ali Duzova

Ali Anarat

Rukshana Shroff

Yelda Bilginer

Salim Caliskan

Cengiz Candan

Jerome Harambat

Zeynep Birsin Özcakar

Oguz Soylemezoglu

Sibylle Tschumi

Sandra Habbig

Ebru Yilmaz

Ayse Balat

Aleksandra Zurowska

Nilgun Cakar

Birgitta Kranz

Pelin Ertan

Anette Melk

Karolis Azukaitis

Franz Schaefer

机构：

[1] Charité - Universitätsmedizin Berlin,Department of Pediatric Pulmonology, Immunology and Intensive Care Medicine

[2] Charité - Universitätsmedizin Berlin,Department of Pediatric Nephrology

[3] University of Heidelberg,Institute of Medical Biometry and Informatics

[4] University Children’s Hospital Heidelberg,Department of General Pediatrics, Division of Inherited Metabolic Diseases

[5] Medical University of Vienna,Division of Pediatric Nephrology and Gastroenterology, Department of Pediatrics and Adolescent Medicine

[6] Cukurova University,Department of Pediatric Nephrology, School of Medicine

[7] The Children’s Memorial Health Institute,Department of Nephrology and Hypertension

[8] Istanbul University Cerrahpasa Faculty of Medicine,Division of Pediatric Nephrology

[9] Ege University Faculty of Medicine,Department of Pediatric Nephrology

[10] Hacettepe University Faculty of Medicine,Division of Pediatric Nephrology, Department of Pediatrics

[11] Great Ormond Street Hospital,Division of Pediatric Nephrology

[12] Hacettepe University Faculty of Medicine,Division of Rheumatology, Department of Pediatrics

[13] Istanbul Medeniyet University,Department of Pediatric Nephrology

[14] Bordeaux University Hospital,Pediatric Nephrology Unit, Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche

[15] Gazi University School of Medicine,Department of Pediatric Nephrology

[16] Inselspital,Division of Pediatric Nephrology

[17] University of Bern,Department of Pediatric Nephrology

[18] University Children’s and Adolescent’s Hospital,Department of Pediatric Nephrology

[19] Sanliurfa Children’s Hospital,Department of Pediatric Nephrology

[20] Istanbul Aydın University,Department of Pediatric Nephrology

[21] Medical University of Gdansk,Department of General Pediatrics, Pediatric Nephrology

[22] Ankara University Faculty of Medicine,Division of Pediatric Nephrology, Department of Pediatrics

[23] University Children’s Hospital Muenster,Department of Pediatric Kidney, Liver and Metabolic Diseases

[24] Medical Faculty of Celal Bayar University,Clinic of Pediatrics, Institute of Clinical Medicine

[25] Hannover Medical School,Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine

[26] Vilnius University,undefined

[27] University Children’s Hospital Heidelberg,undefined

来源：

Pediatric Nephrology | 2019年 / 34卷

关键词：

Uremic toxins; Chronic kidney disease; Cardiovascular disease; Uremia;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：2571 / 2582

页数：11

共 478 条

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[2]

Barreto DV(2015)Meta-analysis of the associations of p-cresyl sulfate (PCS) and indoxyl sulfate (IS) with cardiovascular events and all-cause mortality in patients with chronic renal failure PLoS One 10 e0132589-1514

[3]

Liabeuf S(2013)Renal clearance and intestinal generation of p-cresyl sulfate and indoxyl sulfate in CKD Clin J Am Soc Nephrol 8 1508-498

[4]

Meert N(2016)Uremic solutes in chronic kidney disease and their role in progression PLoS One 11 e0168117-746

[5]

Glorieux G(2016)Role of the gut microbiome in uremia: a potential therapeutic target Am J Kidney Dis 67 483-6

[6]

Temmar M(2016)Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment Nephrol Dial Transplant 31 737-585

[7]

Choukroun G(2013)Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease Am J Nephrol 37 1-1299

[8]

Vanholder R(2012)Cardiovascular disease in children with chronic kidney disease J Am Soc Nephrol 23 578-556

[9]

Massy ZA(2011)Validating a new oscillometric device for aortic pulse wave velocity measurements in children and adolescents Am J Hypertens 24 1294-28

[10]

Lin CJ(2013)Carotid artery intima-media thickness and distensibility in children and adolescents: reference values and role of body dimensions Hypertension 62 550-1483

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