Reconfiguration of the proteasome during chaperone-mediated assembly

被引:0
|
作者
Soyeon Park
Xueming Li
Ho Min Kim
Chingakham Ranjit Singh
Geng Tian
Martin A. Hoyt
Scott Lovell
Kevin P. Battaile
Michal Zolkiewski
Philip Coffino
Jeroen Roelofs
Yifan Cheng
Daniel Finley
机构
[1] Harvard Medical School,Department of Cell Biology
[2] 240 Longwood Avenue,Department of Biochemistry and Biophysics
[3] Boston,Division of Biology
[4] Massachusetts 02115,Department of Microbiology and Immunology
[5] USA,Department of Biochemistry
[6] MCD Biology,undefined
[7] University of Colorado Boulder,undefined
[8] The W.M. Keck Advanced Microscopy Laboratory,undefined
[9] University of California San Francisco,undefined
[10] 600 16th Street,undefined
[11] San Francisco,undefined
[12] California 94158,undefined
[13] USA,undefined
[14] Kansas State University,undefined
[15] 338 Ackert Hall,undefined
[16] Manhattan,undefined
[17] Kansas 66506,undefined
[18] USA,undefined
[19] University of California San Francisco,undefined
[20] 513 Parnassus Avenue,undefined
[21] San Francisco,undefined
[22] California 94143,undefined
[23] USA,undefined
[24] Protein Structure Laboratory,undefined
[25] Del Shankel Structural Biology Center,undefined
[26] University of Kansas,undefined
[27] IMCA-CAT Hauptman-Woodward Medical Research Institute,undefined
[28] 9700 South Cass Avenue,undefined
[29] Building 435A,undefined
[30] Argonne,undefined
[31] Illinois 60439,undefined
[32] USA,undefined
[33] Kansas State University,undefined
[34] 176 Chalmers Hall,undefined
[35] Manhattan,undefined
[36] Kansas 66506,undefined
[37] USA,undefined
[38] Present address: Graduate School of Medical Science and Engineering,undefined
[39] Korea Advanced Institute of Science and Technology,undefined
[40] Daejeon 305-701,undefined
[41] Korea.,undefined
来源
Nature | 2013年 / 497卷
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中图分类号
学科分类号
摘要
The proteasome degrades ubiquitin-conjugated substrates; here, structural and functional insights from studies in yeast reveal that it is reconfigured during chaperone-mediated assembly.
引用
收藏
页码:512 / 516
页数:4
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