Reconfiguration of the proteasome during chaperone-mediated assembly

被引：0

作者：

Soyeon Park

Xueming Li

Ho Min Kim

Chingakham Ranjit Singh

Geng Tian

Martin A. Hoyt

Scott Lovell

Kevin P. Battaile

Michal Zolkiewski

Philip Coffino

Jeroen Roelofs

Yifan Cheng

Daniel Finley

机构：

[1] Harvard Medical School,Department of Cell Biology

[2] 240 Longwood Avenue,Department of Biochemistry and Biophysics

[3] Boston,Division of Biology

[4] Massachusetts 02115,Department of Microbiology and Immunology

[5] USA,Department of Biochemistry

[6] MCD Biology,undefined

[7] University of Colorado Boulder,undefined

[8] The W.M. Keck Advanced Microscopy Laboratory,undefined

[9] University of California San Francisco,undefined

[10] 600 16th Street,undefined

[11] San Francisco,undefined

[12] California 94158,undefined

[13] USA,undefined

[14] Kansas State University,undefined

[15] 338 Ackert Hall,undefined

[16] Manhattan,undefined

[17] Kansas 66506,undefined

[18] USA,undefined

[19] University of California San Francisco,undefined

[20] 513 Parnassus Avenue,undefined

[21] San Francisco,undefined

[22] California 94143,undefined

[23] USA,undefined

[24] Protein Structure Laboratory,undefined

[25] Del Shankel Structural Biology Center,undefined

[26] University of Kansas,undefined

[27] IMCA-CAT Hauptman-Woodward Medical Research Institute,undefined

[28] 9700 South Cass Avenue,undefined

[29] Building 435A,undefined

[30] Argonne,undefined

[31] Illinois 60439,undefined

[32] USA,undefined

[33] Kansas State University,undefined

[34] 176 Chalmers Hall,undefined

[35] Manhattan,undefined

[36] Kansas 66506,undefined

[37] USA,undefined

[38] Present address: Graduate School of Medical Science and Engineering,undefined

[39] Korea Advanced Institute of Science and Technology,undefined

[40] Daejeon 305-701,undefined

[41] Korea.,undefined

来源：

Nature | 2013年 / 497卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

The proteasome degrades ubiquitin-conjugated substrates; here, structural and functional insights from studies in yeast reveal that it is reconfigured during chaperone-mediated assembly.

引用

页码：512 / 516

页数：4

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