Role of creatine kinase and its substrates in the central nervous system in norm and in various pathologies

被引：0
作者：
L. S. Nersesova
机构：
[1] National Academy of Sciences of Republic of Armenia,Institute of Molecular Biology
来源：
Journal of Evolutionary Biochemistry and Physiology | 2011年 / 47卷
关键词：
creatine kinase-creatine phosphate system; creatine; protector action; neurodegenerative diseases;
D O I：
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摘要：
There is presented review of recent publications providing current understanding of role of creatine kinase-creatine phosphate system and creatine, substrate of creatine kinase, in metabolism of cell and specifically of cells of the central nervous system. Particularly noted are the protector role of creatine at mitochondrial and bioenergetic cell dysfunction and potential significance of creatine bioadditions at treatment of neurodegenerative and other diseases.
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