A highly sensitive “turn-on” fluorescent probe for bovine serum albumin protein detection and quantification based on AIE-active distyrylanthracene derivative

被引:0
作者
ZiLong Wang
Ke Ma
Bin Xu
Xing Li
WenJing Tian
机构
[1] Jilin University,State Key Laboratory of Supramolecular Structure and Materials
来源
Science China Chemistry | 2013年 / 56卷
关键词
aggregation-induced emission; fluorescent probe; distyrylanthracene derivative;
D O I
暂无
中图分类号
学科分类号
摘要
A sulfonated 9,10-distyrylanthracene derivative with aggregation-induced emission (AIE) property is designed and synthesized. It shows a highly sensitive and selective fluorescence enhancement property for bovine serum albumin (BSA) protein detection and quantification. Analysis on the interaction between the probe molecule and BSA reveals the essential role of the hydrophobic cavities of the protein folding structure.
引用
收藏
页码:1234 / 1238
页数:4
相关论文
共 156 条
[1]  
Royer CA(2006)Probing protein fording and conformational transitions with fluorescence Chem Rev 106 1769-1784
[2]  
Wang Y(2010)Rhodamine B doped silica nanoparticle labels for protein microarray detection Sci Chi Chem 53 747-751
[3]  
Li ZH(2011)Solid-state electrochemiluminescence protein biosensor with aptamer substitution strategy Sci Chi Chem 54 1109-1115
[4]  
Zhong WY(1993)Effect of native disulfide bonds on the denaturation of proteins in 6 mol/L guanidnium chloride-A fourier transformed infrared study Sci Chi Chem 36 568-574
[5]  
Li H(2010)Protein analysis based on molecular beacon probes and biofunctionalized nanoparticles Sci Chi Chem 53 704-719
[6]  
Xu DK(1999)A luminescent ruthenium complex for ultrasensitive detection of proteins immobilized on membrane supports Anal Biochem 276 129-143
[7]  
Chen HY(2005)Design and synthesis of intramolecular charge transfer-based fluorescent reagents for the highly-sensitive detection of proteins J Am Chem Soc 127 17799-17802
[8]  
Xu Y(2011)Aggregation-induced emission Chem Soc Rev 40 5361-5388
[9]  
Dong P(2007)Aggregationinduced emission: Effects of molecular structure, solid-state conformation, and morphological packing arrangement on light-emitting behaviors of diphenyldibenzofulvene derivatives J Phys Chem C 111 2287-2294
[10]  
Zhang XY(2005)Structures, electronic states, photoluminescence, and carrier transport properties of 1,1-disubstituted 2,3,4,5-tetraphenylsiloles J Am Chem Soc 127 6335-6346