Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-κB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models

被引:0
作者
Vaithinathan Selvaraju
Mahesh Thirunavukkarasu
Mandip Joshi
Babatunde Oriowo
Inam A. Shaikh
Muhammad Tipu Rishi
Leonidas Tapias
Vladimir Coca-Soliz
Ibnalwalid Saad
Jacob Campbell
Seetur R. Pradeep
Santosh Swaminathan
Siu-Pok Yee
David W. McFadden
J. Alexander Palesty
Nilanjana Maulik
机构
[1] University of Connecticut School of Medicine,Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory
[2] University of Connecticut Health,Department of Surgery
[3] University of Connecticut Health,Department of Surgery
[4] Saint Mary’s Hospital,undefined
[5] Center for Mouse Genome Modification,undefined
[6] University of Connecticut Health,undefined
来源
Basic Research in Cardiology | 2020年 / 115卷
关键词
Myocardial infarction; cIAP2; Hindlimb ischemia; Angiogenesis; NF-κB;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 486 条
  • [11] Maulik N(2016)IAPs and cell migration Med Sci Monit 22 2324-2334
  • [12] Adluri RS(1993)Effects of rosuvastatin and MiR-126 on myocardial injury induced by acute myocardial infarction in rats: role of vascular endothelial growth factor a (VEGF-A) Eur Heart J 14 25-30
  • [13] Thirunavukkarasu M(1996)Myocardial damage during ischaemia and reperfusion Mol Cell Biol 16 4604-4613
  • [14] Zhan L(2010)Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 PLoS ONE 5 e11260-335
  • [15] Akita Y(2010)Efficient generation of germ line transmitting chimeras from C57BL/6 N ES cells by aggregation with outbred host embryos Angiogenesis 13 327-138
  • [16] Samuel SM(1999)Targeting NF-kappaB in infantile hemangioma-derived stem cells reduces VEGF-A expression Mech Dev 81 127-368
  • [17] Otani H(1997)Oligomerisation of tube and pelle leads to nuclear localisation of dorsal J Cell Sci 110 357-574
  • [18] Ho YS(2010)Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27 Nat Rev Cancer 10 561-18028
  • [19] Maulik G(2000)IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer J Biol Chem 275 18022-4955
  • [20] Maulik N(2014)Involvement of two NF-kappa B binding elements in tumor necrosis factor alpha -, CD40-, and epstein-barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene Biochemistry 53 4946-202