LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

被引：0
|
作者：
Peng Xu
Da-xiong Feng
Jun Wang
Yao-Dong Wang
Gang Xie
Bin Zhang
Xiao-Han Li
Jia-Wei Zeng
Jia-Fu Feng
机构：
[1] NHC Key Laboratory of Nuclear Technology Medical Transformation (MIANYANG CENTRAL HOSPITAL),Department of Clinical Laboratory, Mianyang Central Hospital, School of Medicine
[2] Mianyang Central Hospital,Department of Spine Surgery
[3] School of Medicine,Department of Laboratory Medicine
[4] University of Electronic Science and Technology of China,Department of Urology Surgery, Mianyang Central Hospital, School of Medicine
[5] University of Electronic Science and Technology of China,Department of Pathology, Mianyang Central Hospital, School of Medicine
[6] The Affiliated Hospital of Southwest Medical University,Department of Medical Laboratory
[7] Sichuan Provincial Maternity and Child Health Care Hospital,undefined
[8] University of Electronic Science and Technology of China,undefined
[9] University of Electronic Science and Technology of China,undefined
[10] The Affiliated Hospital of Southwest Medical University,undefined
来源：
Cancer Cell International | / 23卷
关键词：
Renal cell carcinoma; N6-methyladenosine; Long non-coding RNA; AGAP2-AS1; IGF2BP3; miR-9-5p; THBS2; PI3K/AKT; M2 polarization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 20 条
  • [1] LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway
    Xu, Peng
    Feng, Da-xiong
    Wang, Jun
    Wang, Yao-Dong
    Xie, Gang
    Zhang, Bin
    Li, Xiao-Han
    Zeng, Jia-Wei
    Feng, Jia-Fu
    CANCER CELL INTERNATIONAL, 2023, 23 (01)
  • [2] Insulin-like growth factor 2 mRNA-binding protein 3 enhanced melanoma migration through regulation of AKT1 and RELA expression
    Sheen, Yi-Shuan
    Syu, Yan-Jie
    Chang, Yu-Chuan
    Hsieh, Ping-Han
    Liao, Yi-Hua
    Lin, Ming-Hsien
    Chen, Chien-Yu
    Chu, Chia-Yu
    Chu, Chia-Ying
    EXPERIMENTAL DERMATOLOGY, 2024, 33 (01)
  • [3] Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27Kip1
    Endo, Ihiro
    Amatya, Vishwa Jeet
    Kushitani, Kei
    Kambara, Takahiro
    Nakagiri, Tetsuya
    Fujii, Yutaro
    Takeshima, Yukio
    FRONTIERS IN ONCOLOGY, 2022, 11
  • [4] Insulin-Like Growth Factor II mRNA-Binding Protein 3 Expression Promotes Cell Migration through NF-κB Pathway and Predicts Poor Prognosis in Localized Clear Cell Renal Cell Carcinoma
    Pei, X.
    Li, M.
    Zham, J.
    Zhou, M.
    Zhang, H.
    He, H.
    MODERN PATHOLOGY, 2014, 27 : 253A - 253A
  • [5] Insulin-Like Growth Factor II mRNA-Binding Protein 3 Expression Promotes Cell Migration through NF-κB Pathway and Predicts Poor Prognosis in Localized Clear Cell Renal Cell Carcinoma
    Pei, X.
    Li, M.
    Zhan, J.
    Zhou, M.
    Zhang, H.
    He, H.
    LABORATORY INVESTIGATION, 2014, 94 : 253A - 253A
  • [6] MicroRNA-454-3p inhibits cell proliferation and invasion in esophageal cancer by targeting insulin-like growth factor 2 mRNA-binding protein 1
    Yan, Aiting
    Wang, Cuizhu
    Zheng, Liangfeng
    Zhou, Jiebo
    Zhang, Yan
    ONCOLOGY LETTERS, 2020, 20 (06)
  • [7] Insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor cell migration through NF-κB pathway and predicts poor prognosis in localized clear cell renal cell carcinoma
    Pei, Xuelian
    Li, Muhan
    Zhou, Ming
    Aydin, Hakan
    Zhan, Jun
    Yu, Yu
    Hu, Jinxia
    Guan, Lizhao
    He, Huiying
    Zhang, Hongquan
    CLINICAL & EXPERIMENTAL METASTASIS, 2015, 32 (03) : 206 - 206
  • [8] Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation via activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer
    Bai-Shun Wan
    Ming Cheng
    Ling Zhang
    World Journal of Gastroenterology, 2019, 25 (40) : 6063 - 6076
  • [9] Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation via activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer
    Wan, Bai-Shun
    Cheng, Ming
    Zhang, Ling
    WORLD JOURNAL OF GASTROENTEROLOGY, 2019, 25 (40) : 6063 - 6076
  • [10] Exosomal lncRNA HOTAIR induce macrophages to M2 polarization via PI3K/p-AKT/AKT pathway and promote EMT and metastasis in laryngeal squamous cell carcinoma
    Wang, Jingting
    Wang, Nan
    Zheng, Zeyu
    Che, Yanlu
    Suzuki, Masanobu
    Kano, Satoshi
    Lu, Jianguang
    Wang, Peng
    Sun, Yanan
    Homma, Akihiro
    BMC CANCER, 2022, 22 (01)
12