Preventing chronicity of migraine

被引：22
作者：
Fanciullacci M. [1 ]
De Cesaris F. [1 ]
机构：
[1] Headache Center, Department of Internal Medicine, University of Florence, I-50139 Firenze
来源：
The Journal of Headache and Pain | 2005年 / 6卷 / 4期
关键词：
Central sensitisation; Chronic migraine; Disease progression; Medication overuse; Risk factor;
D O I：
10.1007/s10194-005-0224-8
中图分类号：
学科分类号：
摘要：
Chronic migraine and transformed migraine are conditions with a progression from episodic to chronic headache, a disabling stage. During attack, cutaneous allodynia frequently occurs: it reflects sensitisation of the central neurons of the trigeminovascular system. Early triptan therapy (prior to the development of central sensitisation) may protect from the chronicisation of migraine. In addition, early recognition of non-headache changes in neurologic function between episodes of headache offers a sensitive indicator of headache transformation. Attack frequency is the stronger predictor for migraine progression: prophylactic agents could be administered to patients with a high number of attacks. Medication over use is the most important iatrogenic risk factor for the acceleration of disease and it must be prevented; other important risk factors are female sex, obesity and stressful life events. © Springer-Verlag Italia 2005.
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页码：331 / 333
页数：2
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