Optimizing Supercritical Fluid Extraction of Usnic Acid from the Lichen Species Usnea subfloridana

被引：11

作者：

Boitsova, T. A. ^{[1
]}

Brovko, O. S. ^{[1
]}

Ivakhnov, A. D. ^{[1
,2
]}

Zhil'tsov, D. V. ^{[1
]}

机构：

[1] Russian Acad Sci, Fed Ctr Integrated Arctic Res, Arkhangelsk 163000, Russia

[2] Lomonosov Northern Arctic Fed Univ, Arkhangelsk 163002, Russia

来源：

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B | 2020年 / 14卷 / 07期

基金：

俄罗斯基础研究基金会;

关键词：

Keywords; lichen; Usnea subfloridana; usnic acid; supercritical fluid extraction; rotatable composite design with uniform precision;

D O I：

10.1134/S1990793120070040

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

Supercritical fluid extraction of usnic acid (UA) from the lichen species Usnea subfloridana is optimized using a rotatable second-order composite design with uniform precision. The effect that the pressure, temperature, and the process duration have on the extract yield is evaluated. The following optimal values for the extraction parameters are established based on the developed model: extraction duration, 80 min; temperature, 85 degrees C; and pressure, 150 atm. Under these conditions, the predicted extract yield (1.19%) agrees closely with the experimental value (1.11%). The prepared extract exhibits antibacterial activity against the bacterium Escherichia coli and microorganisms of the species Staphylococcus aureus and Bacillus subtilis.

引用

页码：1135 / 1141

页数：7

共 24 条

[1] Optimisation of the extraction of pomegranate (Punica granatum) husk phenolics using water/ethanol solvent systems and response surface methodology [J].

Amyrgialaki, Eleni ;

Makris, Dirrlitris P. ;

Mauromoustakos, Andy ;

Kefalas, Panagiotis .

INDUSTRIAL CROPS AND PRODUCTS, 2014, 59 :216-222

[2]

[Anonymous], 2016, RF Patent, Patent No. 2582978

[3]

[Anonymous], 1984, WOOD CHEM ULTRASTRUC, DOI DOI 10.1515/9783110839654

[4] Supercritical Fluid Extraction of Usnic Acid from Lichen of Cladonia Genus [J].

Brovko, O. S. ;

Ivakhnov, A. D. ;

Palamarchuk, I. A. ;

Boitsova, T. A. .

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 11 (08) :1306-1311

[5]

Brovko O.S., 2016, USP SOVREM ESTESTVOZ, P20

[6]

Cansaran D, 2006, Z NATURFORSCH C, V61, P47

[7] Optimization of ultrasound extraction condition of phospholipids from palm-pressed fiber [J].

Chua, Seong Chea ;

Tan, Chin Ping ;

Mirhosseini, Hamed ;

Lai, Oi Ming ;

Long, Kamariah ;

Baharin, Badlishah Sham .

JOURNAL OF FOOD ENGINEERING, 2009, 92 (04) :403-409

[8] Optimization of Ultrasound-Assisted Extraction of Phenolic Compounds, Antioxidants, and Anthocyanins from Grape (Vitis vinifera) Seeds [J].

Ghafoor, Kashif ;

Choi, Yong Hee ;

Jeon, Ju Yeong ;

Jo, In Hee .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (11) :4988-4994

[9] Usnic acid [J].

Ingólfsdóttir, K .

PHYTOCHEMISTRY, 2002, 61 (07) :729-736

[10] Optimization of Oil Extraction from Rowanberry Waste in Alcoholic Beverage Production [J].

Ivakhnov, A. D. ;

Sadkova, K. S. ;

Sobashnikova, A. S. ;

Skrebets, T. E. .

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2019, 13 (07) :1135-1138

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