A DSC and Raman spectroscopic study of microspheres preparedwith polar cosolvents by different techniques

被引：0
|
作者：
P. Sipos
A. Szabó
I. Erős
Piroska Szabó-Révész
机构：
[1] University of Szeged,Department of Pharmaceutical Technology
[2] Budapest University of Technology and Economics,Department of Organic Chemistry and Technology
来源：
Journal of Thermal Analysis and Calorimetry | 2008年 / 94卷
关键词：
cosolvents; DSC; energy-dispersive X-ray fluorescence analysis; microsphere; Raman spectroscopy; spray drying; W/O/W multiple emulsion;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A study was made of the possibilities of gradually decreasing the concentration of the toxic organic solvent in the process of microsphere preparation. Ammonio methacrylate copolymer-based microspheres were prepared by spray drying or conventional solvent evaporation techniques, and compared. The formulations were designed by varying the preparation methods and the concentrations of four polar cosolvents as independent variables.
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页码：109 / 118
页数：9
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