Quality control of teraphthal production. 1. Chemical composition

被引：0

作者：

Goizman M.S. ^{[1
]}

Degterev E.V. ^{[2
]}

Turchin K.F. ^{[2
]}

Arzamastsev A.P. ^{[3
]}

机构：

[1] Research Institute of Organic Intermediates and Dyes, State Scientific Center of the Russian Federation, Moscow

[2] Center for Drug Chemistry, All-Russia Research Institute of Pharmaceutical Chemistry, Moscow

[3] Sechenov Medical Academy, Moscow

来源：

Pharmaceutical Chemistry Journal | 2007年 / 41卷 / 12期

关键词：

Cobalt; Phthalocyanine; Proton Magnetic Resonance Spectrum; Broad Resonance; Component Composition;

D O I：

10.1007/s11094-008-0035-8

中图分类号：

学科分类号：

摘要：

It is shown that the drug teraphthal should be considered as a mixture of the octasodium salt of cobalt(II) 2,3,9,10,16,17,23,24-octacarboxyphthalocyanine (OCPC) and its oxidation product (component A) with the octasodium salt of OCPC and products from the extensive destruction of a substance with a similar elemental composition (component B). The composition can be estimated quantitatively using (i) the results of elemental analysis (H, N, Co) and (ii) PMR in combination with measurement of the weight loss on drying. © 2007 Springer Science+Business Media, Inc.

引用

页码：670 / 675

页数：5