Hypoxic metabolism in human hematopoietic stem cells

被引：0
作者：
Fatih Kocabas
Li Xie
Jingjing Xie
Zhuo Yu
Ralph J. DeBerardinis
Wataru Kimura
SuWannee Thet
Ahmed F. Elshamy
Hesham Abouellail
Shalini Muralidhar
Xiaoye Liu
Chiqi Chen
Hesham A. Sadek
Cheng Cheng Zhang
Junke Zheng
机构：
[1] UT Southwestern Medical Center at Dallas,Department of Internal Medicine, Division of Cardiology
[2] Yeditepe University,Department of Genetics and Bioengineering, Faculty of Engineering
[3] Shanghai Jiao Tong University School of Medicine,Hongqiao International Institute of Medicine, Shanghai Tongren Hospital / Faculty of Basic Medicine
[4] Shanghai Jiao Tong University School of Medicine,Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education
[5] Bingzhou Medical University,Departments of Pediatrics and Genetics
[6] Taishan Scholar Program,Departments of Physiology and Developmental Biology
[7] UT Southwestern Medical Center at Dallas,undefined
[8] Department of Clinical Pathology,undefined
[9] El Galaa Hospital,undefined
[10] Faculty of Medicine Ain Shams University,undefined
[11] UT Southwestern Medical Center at Dallas,undefined
来源：
Cell & Bioscience | / 5卷
关键词：
Stem cells; Metabolism; Hypoxia; Hypoxic regulation of metabolism; Human hematopoietic progenitor and stem cells; HPSCs;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 235 条
[1]  
Eliasson P(2010)The hematopoietic stem cell niche: low in oxygen but a nice place to be J Cell Physiol 222 17-22
[2]  
Jonsson JI(2011)Dynamic niches in the origination and differentiation of haematopoietic stem cells Nat Rev Mol Cell Biol 12 643-55
[3]  
Wang LD(2010)The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche Cell Stem Cell 7 380-90
[4]  
Wagers AJ(2010)Regulation of the HIF-1alpha level is essential for hematopoietic stem cells Cell Stem Cell 7 391-402
[5]  
Simsek T(2006)Profiling of differentially expressed genes in human stem cells by cDNA microarray Mol Cells 21 343-55
[6]  
Kocabas F(2006)HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Cell Metab 3 187-97
[7]  
Zheng JK(2006)HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia Cell Metab 3 177-85
[8]  
DeBerardinis RJ(2009)HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms Mini Rev Med Chem 9 1084-101
[9]  
Mahmoud AI(2007)HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity Cancer Cell 11 407-20
[10]  
Olson EN(2009)Regulation of cancer cell metabolism by hypoxia-inducible factor 1 Semin Cancer Biol 19 12-6
12345678910