Cholangiocarcinoma in primary sclerosing cholangitis

被引:17
作者
Abbas G. [1 ]
Lindor K.D. [1 ]
机构
[1] Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, 20 First Street, SW
关键词
Cholangiocarcinoma; Diagnosis; Epidemiology; Primary sclerosing cholangitis; Treatment;
D O I
10.1007/s12029-009-9085-8
中图分类号
学科分类号
摘要
Introduction: Cholangiocarcinoma (CCA) is an aggressive and nearly always fatal tumor of the biliary tract. Purpose: This review explores risk factors, epidemiology, current diagnostic approaches, and treatment of CCA arising in patients with primary sclerosing cholangitis (PSC). Methods: We review latest recommendations about screening strategies to enable the early detection of CCA in PSC, using CA 19-9 and ultrasound imaging, as well as fluorescent in situ hybridization techniques to enhance the accuracy of biliary cytology. We also review the emerging role of liver transplantation. © 2009 Humana Press Inc.
引用
收藏
页码:19 / 25
页数:6
相关论文
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