A pathogenetic role for IL-21 in primary Sjögren syndrome

被引：0
|
作者：
Seung-Ki Kwok
Jennifer Lee
Di Yu
Kwi Young Kang
Mi-La Cho
Hae-Rim Kim
Ji Hyeon Ju
Sang-Heon Lee
Sung-Hwan Park
Ho-Youn Kim
机构：
[1] Seoul St Mary's Hospital,Division of Rheumatology, Department of Internal Medicine
[2] College of Medicine,Division of Rheumatology, Department of Internal Medicine
[3] The Catholic University of Korea,undefined
[4] The Rheumatism Research Centre,undefined
[5] Catholic Research Institute of Medical Science,undefined
[6] The Catholic University of Korea,undefined
[7] Laboratory for Molecular Immunomodulation,undefined
[8] School of Biomedical Sciences,undefined
[9] Monash University,undefined
[10] Konkuk University School of Medicine,undefined
[11] Konkuk University Medical Centre,undefined
来源：
Nature Reviews Rheumatology | 2015年 / 11卷
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摘要：
Kim et al. hypothesize that IL-21 is crucial to the pathogenesis of primary Sjögren syndrome (pSS), focusing on evidence of an interplay between the innate and adaptive immune responses mediated by the effects of IL-21 on immune cells. This new perspective might ultimately offer insight into novel approaches to the treatment of pSS.
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页码：368 / 374
页数：6
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