Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding

被引：0
作者：
Nicola Laurieri
Akane Kawamura
Isaac M Westwood
Amy Varney
Elizabeth Morris
Angela J Russell
Lesley A Stanley
Edith Sim
机构：
[1] University of Oxford,Department of Pharmacology
[2] Chemistry Research Laboratory,Department of Chemistry
[3] University of Oxford,Divisions of Structural Biology and Cancer Therapeutics
[4] The Institute of Cancer Research,Faculty of Science, Engineering and Computing
[5] Chester Beatty Laboratories,undefined
[6] Consultant in Investigative Toxicology,undefined
[7] Kingston University,undefined
来源：
BMC Pharmacology and Toxicology | / 15卷
关键词：
Arylamine ; -acetyltransferase; (MOUSE)NAT1; (MOUSE)NAT2; Substrate specificity; Inhibitor selectivity; Structural docking;
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