Isolation and Expression Analysis of the Testis-Specific Gene, STRA8, Stimulated by Retinoic Acid Gene 8

被引：0
作者：
Toshinobu Miyamoto
Kazuo Sengoku
Naoyuki Takuma
Shiga Hasuike
Hiroaki Hayashi
Tomofumi Yamauchi
Tsuyoshi Yamashita
Mutsuo Ishikawa
机构：
[1] Asahikawa Medical College,Department of Obstetrics and Gynecology
来源：
Journal of Assisted Reproduction and Genetics | 2002年 / 19卷
关键词：
Spermatogenesis; STRA8; testis;
D O I：
暂无
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学科分类号：
摘要：
Retinoids are known to be required for vertebrate reproduction, and in the male, for the maintenance of normal testicular structure and function. Previously several novel retinoic acid responsive genes, collectively designated as the Stra genes, had been isolated in the mouse. The Stra8 gene encodes a cytoplasmic protein and is expressed specific to the developing male gonad during mouse embryogenesis. In adult mouse, its expression is restricted to the premeiotic germ cells. Thus it has been suggested that the mouse Stra8 protein may play a role in the premeiotic phase of spermatogenesis.
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页码：531 / 535
页数：4
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