Efficacy of aerobic physical retraining in a case of combined pulmonary fibrosis and emphysema syndrome: A case report

被引：4

作者：

De Simone G. ^{[2
]}

Aquino G. ^{[1
]}

Di Gioia C. ^{[2
]}

Mazzarella G. ^{[3
]}

Bianco A. ^{[1
]}

Calcagno G. ^{[1
]}

机构：

[1] Department of Medicine and Health Sciences, V Tiberio University of Molise, Campobasso

[2] Institute of Rehabilitation Villa Margherita Benevento, Unit of Cardiology and Pneumology, Benevento

[3] Department of Cardio-Thoracic and Respiratory Sciences, Second University of Napoli, Napoli

来源：

Journal of Medical Case Reports | / 9卷 / 1期

关键词：

Aerobic physical retraining; Combined pulmonary fibrosis and emphysema; CPFE; Pulmonary rehabilitation;

D O I：

10.1186/s13256-015-0570-3

中图分类号：

学科分类号：

摘要：

Introduction: Combined pulmonary fibrosis and emphysema has recently been recognized as a syndrome but remains under-diagnosed. Neither clinical management nor therapeutic approaches have been clearly defined. Pulmonary rehabilitation has not been considered within the therapeutic options for combined pulmonary fibrosis and emphysema. In this case we explored the potential benefits of a specific aerobic physical retraining program in the management of combined pulmonary fibrosis and emphysema. Case presentation: We describe the case of a 65-year-old Caucasian man with combined pulmonary fibrosis and emphysema and respiratory failure who was receiving long-term oxygen therapy. Our patient underwent physica retraining with moderate intensity aerobic and breathing exercises for four weeks. Clinical and motor tests, as well as questionnaires assessing quality of life and depression levels, were performed prior to and following the retraining. At the end of the retraining program a relevant reduction of long-term oxygen therapy requirement was registered; improvements in terms of physical performance, quality of life, and mood were observed in our patient but no change in respiratory parameters. Conclusions: A program of aerobic physical retraining appears to be beneficial to patients with combined pulmonary fibrosis and emphysema and may be considered as an additional therapeutic option. © 2015 De Simone et al.; licensee BioMed Central.

引用

共 15 条

[1]

Cottin V., Nunes H., Brillet P., Combined pulmonary fibrosis and emphysema: A distinct underrecognised entity, Eur Respir J., 26, pp. 586-593, (2005)

[2]

Chilosi M., Poletti V., Rossi A., The pathogenesis of COPD and IPF: Distinct horns of the same devil?, Respir Res., 13, (2012)

[3]

Mazzarella G., Esposito V., Bianco A., Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens, Environ Pollut., 161, pp. 64-69, (2012)

[4]

Esposito V., Lucariello A., Savarese L., Morphology changes in human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM1.0) and pollen allergens, Environ Pollut., 171, pp. 162-167, (2012)

[5]

Katzenstein A.L., Mukhopadhyay S., Zanardi C., Clinically occult interstitial fibrosis in smokers: Classification significance of a surprisingly common finding in lobectomy specimens, Hum Pathol., 41, 3, pp. 316-325, (2010)

[6]

De Laurentiis G., Paris D., Melck D., Separating smoking-related diseases using NMR-based metabolomics of exhaled breath condensate, J Proteome Res., 12, pp. 1502-1511, (2013)

[7]

Maldor M.J., Kufel T.J., Pineda L.A., Effect of pulmonary rehabilitation on quadriceps fatigability during exercise, Am J Respir Crit Care Med., 163, pp. 930-935, (2001)

[8]

Decramer M., Response of the respiratory muscles to rehabilitation in COPD, J Appl Physiol., 107, pp. 971-976, (2009)

[9]

Mereles D., Ehlken N., Kreuscher S., Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension, Circulation, 114, pp. 1482-1489, (2006)

[10]

Daniele A., De Rosa A., Nigro E., Adiponectin oligomerization state and adiponectin receptors airway expression in chronic obstructive pulmonary disease, Int J Biochem Cell Biol., 44, pp. 563-569, (2012)

← 1 2 →