Pharmacokinetic Considerations for Antimicrobial Therapy in Patients Receiving Renal Replacement Therapy

被引：0

作者：

Federico Pea

Pierluigi Viale

Federica Pavan

Mario Furlanut

机构：

[1] University of Udine,Institute of Clinical Pharmacology and Toxicology, Department of Experimental and Clinical Pathology and Medicine, Medical School

[2] University of Udine,Clinic of Infectious Diseases, Department of Medical and Morphological Research, Medical School

[3] University of Udine,Institute of Clinical Pharmacology and Toxicology, DPMSC

来源：

Clinical Pharmacokinetics | 2007年 / 46卷

关键词：

Renal Replacement Therapy; Linezolid; Meropenem; Therapeutic Drug Monitoring; Colistin;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Continuous renal replacement therapy (CRRT), particularly continuous venovenous haemofiltration (CVVH) and continuous venovenous haemodiafiltration (CVVHDF), are gaining increasing relevance in routine clinical management of intensive care unit patients. The application of CRRT, by leading to extracorporeal clearance (CLCRRT), may significantly alter the pharmacokinetic behaviour of some drugs. This may be of particular interest in critically ill patients presenting with life-threatening infections, since the risk of underdosing with antimicrobial agents during this procedure may lead to both therapeutic failure and the spread of breakthrough resistance. The intent of this review is to discuss the pharmacokinetic principles of CLCRRT of antimicrobial agents during the application of CVVH and CVVHDF and to summarise the most recent findings on this topic (from 1996 to December 2006) in order to understand the basis for optimal dosage adjustments of different antimicrobial agents.

引用

页码：997 / 1038

页数：41

共 50 条

[41] Efficacy of immediate versus delayed renal replacement therapy in septic patients undergoing continuous renal replacement therapy [J].

Ding, Guorong ;

Qiu, Pingfeng ;

Jin, Peng ;

Xie, Yanzhong ;

Zhang, Shanjing ;

Lou, Qiaoqin .

AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2024, 16 (08) :3646-3653

[42] Therapeutic Drug Monitoring of Antibiotic Drugs in Patients Receiving Continuous Renal Replacement Therapy or Intermittent Hemodialysis: A Critical Review [J].

Matusik, Elodie ;

Boidin, Clement ;

Friggeri, Arnaud ;

Richard, Jean-Christophe ;

Bitker, Laurent ;

Roberts, Jason A. ;

Goutelle, Sylvain .

THERAPEUTIC DRUG MONITORING, 2022, 44 (01) :86-102

[43] Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines? [J].

Jason A Roberts ;

Darren M Roberts .

Critical Care, 18

[44] Pharmacokinetic/pharmacodynamic analysis of linezolid in critically ill patients with severe sepsis treated with renal replacement therapy [J].

H Barrasa González ;

A Martín López ;

A Isla Ruiz ;

A Rodríguez Gascón ;

A Soraluce Olañeta ;

JA Sánchez Izquierdo ;

F Muñoyerro González ;

A Rodríguez Oviedo ;

S Castaño Ávila ;

F Fonseca San Miguel ;

FJ Maynar Moliner .

Intensive Care Medicine Experimental, 3 (Suppl 1)

[45] High-dose colistin pharmacokinetics in critically ill patients receiving continuous renal replacement therapy [J].

De Pascale, Gennaro ;

Lisi, Lucia ;

Cutuli, Salvatore Lucio ;

Marinozzi, Carlotta ;

Palladini, Altea ;

Ferrando, Elena Sancho ;

Tanzarella, Eloisa Sofia ;

Lombardi, Gianmarco ;

Grieco, Domenico Luca ;

Caroli, Alessandro ;

Xhemalaj, Rikardo ;

Cascarano, Laura ;

Ciotti, Gabriella Maria Pia ;

Sandroni, Claudio ;

Sanguinetti, Maurizio ;

Navarra, Pierluigi ;

Antonelli, Massimo .

ANNALS OF INTENSIVE CARE, 2024, 14 (01)

[46] Associations of continuous anionic gap detection with the mortality in critically ill patients receiving renal replacement therapy [J].

Zhai, Yiling ;

Luo, Changjun ;

Zhou, Tao ;

Zeng, Guangzhi ;

Huang, Qiongyan ;

Li, Jun .

INTERNATIONAL UROLOGY AND NEPHROLOGY, 2023, 55 (11) :2967-2980

[47] Blood culture collection in patients with acute kidney injury receiving renal replacement therapy: an observational study [J].

Ostrowski, J. ;

Paterson, D. L. ;

Lipman, J. ;

Udy, A. A. .

ANAESTHESIA AND INTENSIVE CARE, 2012, 40 (05) :813-819

[48] Development of Vancomycin Dose Individualization Strategy by Bayesian Prediction in Patients Receiving Continuous Renal Replacement Therapy [J].

Oda, Kazutaka ;

Jono, Hirofumi ;

Kamohara, Hidenobu ;

Nishi, Kazuhiko ;

Tanoue, Naomi ;

Saito, Hideyuki .

PHARMACEUTICAL RESEARCH, 2020, 37 (06)

[49] Development of Vancomycin Dose Individualization Strategy by Bayesian Prediction in Patients Receiving Continuous Renal Replacement Therapy [J].

Kazutaka Oda ;

Hirofumi Jono ;

Hidenobu Kamohara ;

Kazuhiko Nishi ;

Naomi Tanoue ;

Hideyuki Saito .

Pharmaceutical Research, 2020, 37

[50] Associations of continuous anionic gap detection with the mortality in critically ill patients receiving renal replacement therapy [J].

Yiling Zhai ;

Changjun Luo ;

Tao Zhou ;

Guangzhi Zeng ;

Qiongyan Huang ;

Jun Li .

International Urology and Nephrology, 2023, 55 :2967-2980

← 1 2 3 4 5 →