Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

被引:0
作者
Jun Wu
Carl Ekman
Andreas Jönsen
Gunnar Sturfelt
Anders A Bengtsson
Anders Gottsäter
Bengt Lindblad
Elisabet Lindqvist
Tore Saxne
Björn Dahlbäck
机构
[1] Skåne University Hospital,Department of Laboratory Medicine, Section of Clinical Chemistry, Lund University, Wallenberg Laboratory
[2] Lund University,Department of Clinical Sciences, Section of Rheumatology
[3] Skåne University Hospital,Department of Clinical Sciences, Vascular Center
[4] Lund University,Department of Laboratory Medicine
[5] Skåne University Hospital,undefined
[6] People's Hospital,undefined
[7] Peking University,undefined
来源
Arthritis Research & Therapy | / 13卷
关键词
Systemic Lupus Erythematosus; Nephritis; Systemic Lupus Erythematosus Patient; Lupus Nephritis; Critical Limb Ischemia;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 249 条
  • [1] Linger RM(2008)TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer Adv Cancer Res 100 35-83
  • [2] Keating AK(2008)Immunobiology of the TAM receptors Nat Rev Immunol 8 327-336
  • [3] Earp HS(2006)Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily FEBS J 273 5231-5244
  • [4] Graham DK(2006)Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases Cytokine Growth Factor Rev 17 295-304
  • [5] Lemke G(2009)The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells Clin Immunol 133 138-144
  • [6] Rothlin CV(2010)Mertk in daily retinal phagocytosis: a history in the making Adv Exp Med Biol 664 133-140
  • [7] Hafizi S(2007)TAM receptors are pleiotropic inhibitors of the innate immune response Cell 131 1124-1136
  • [8] Dahlback B(2004)The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically? Immunology 113 1-14
  • [9] Hafizi S(2002)Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase J Exp Med 196 135-140
  • [10] Dahlback B(2007)A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation Blood 109 1026-1033