Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

被引:0
作者
Martin Philpott
Catherine M Rogers
Clarence Yapp
Chris Wells
Jean-Philippe Lambert
Claire Strain-Damerell
Nicola A Burgess-Brown
Anne-Claude Gingras
Stefan Knapp
Susanne Müller
机构
[1] University of Oxford,Structural Genomics Consortium, Nuffield Department of Clinical Medicine
[2] Old Road Campus Research Building,Target Discovery Institute, Nuffield Department of Clinical Medicine
[3] University of Oxford,Lunenfeld
[4] Mount Sinai Hospital,Tanenbaum Research Institute
[5] University of Toronto,Department of Molecular Genetics
[6] University of Oxford,Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences
[7] Cardiff University,Nanotether Discovery Sciences Ltd, Museum Avenue
来源
Epigenetics & Chromatin | / 7卷
关键词
Bromodomain; Cell-based assay; Confocal microscopy; Epigenetics; Fluorescence recovery after photobleaching; Histone acetylation; Small-molecule inhibitor;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 46 条
[31]   Application of fluorescence recovery after photobleaching to study prestin lateral mobility in the human embryonic kidney cell [J].
Organ, Louise E. ;
Raphael, Robert M. .
JOURNAL OF BIOMEDICAL OPTICS, 2007, 12 (02)
[32]   Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching [J].
Kuzma-Kuzniarska, Maria ;
Yapp, Clarence ;
Pearson-Jones, Thomas W. ;
Jones, Andrew K. ;
Hulley, Philippa A. .
JOURNAL OF BIOMEDICAL OPTICS, 2014, 19 (01)
[33]   Measuring Exocytosis Rate Using Corrected Fluorescence Recovery After Photoconversion [J].
Luo, Nan ;
Yan, An ;
Yang, Zhenbiao .
TRAFFIC, 2016, 17 (05) :554-564
[34]   Field and pore size dependence of the electrophoretic mobility of DNA: A combination of fluorescence recovery after photobleaching and electric birefringence measurements [J].
Tinland, B ;
Pernodet, N ;
Weill, G .
ELECTROPHORESIS, 1996, 17 (06) :1046-1051
[35]   Use of metabolomics and fluorescence recovery after photobleaching to study the bioavailability and intestinal mucus diffusion of polyphenols from cauliflower waste [J].
Gonzales, Gerard Bryan ;
Smagghe, Guy ;
Mackie, Alan ;
Grootaert, Charlotte ;
Bajka, Balazs ;
Rigby, Neil ;
Raes, Katleen ;
Van Camp, John .
JOURNAL OF FUNCTIONAL FOODS, 2015, 16 :403-413
[36]   Fluorescence Recovery after Photobleaching of Yellow Fluorescent Protein Tagged p62 in Aggresome-like Induced Structures [J].
Rademacher, David J. ;
Cabe, Maleen ;
Bakowska, Joanna C. .
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2019, (145)
[37]   Identification of novel bromodomain inhibitors of Trypanosoma cruzi bromodomain factor 2 (TcBDF2) using a fluorescence polarization-based high-throughput assay [J].
Tavernelli, Luis E. ;
Alonso, Victoria L. ;
Pena, Imanol ;
Araya, Elvio Rodriguez ;
Manarin, Romina ;
Cantizani, Juan ;
Martin, Julio ;
Salamanca, Juan ;
Bamborough, Paul ;
Calderon, Felix ;
Gabarro, Raquel ;
Serra, Esteban .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2024, 68 (08)
[38]   Fluorescence recovery after photobleaching reveals high cycling dynamics of plasma membrane aquaporins in Arabidopsis roots under salt stress [J].
Luu, Doan-Trung ;
Martiniere, Alexandre ;
Sorieul, Mathias ;
Runions, John ;
Maurel, Christophe .
PLANT JOURNAL, 2012, 69 (05) :894-905
[39]   Fluorescence recovery after photobleaching on the confocal laser-scanning microscope: generalized model without restriction on the size of the photobleached disk [J].
Smisdom, Nick ;
Braeckmans, Kevin ;
Deschout, Hendrik ;
vandeVen, Martin ;
Rigo, Jean-Michel ;
De Smedt, Stefaan C. ;
Ameloot, Marcel .
JOURNAL OF BIOMEDICAL OPTICS, 2011, 16 (04)
[40]   Image-based Fluorescence Recovery After Photobleaching (FRAP) to dissect vancomycin diffusion-reaction processes in Staphylococcus aureus biofilms [J].
Oubekka, S. Daddi ;
Briandet, R. ;
Waharte, F. ;
Fontaine-Aupart, M. -P. ;
Steenkeste, K. .
CLINICAL AND BIOMEDICAL SPECTROSCOPY AND IMAGING II, 2011, 8087