Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

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作者
Martin Philpott
Catherine M Rogers
Clarence Yapp
Chris Wells
Jean-Philippe Lambert
Claire Strain-Damerell
Nicola A Burgess-Brown
Anne-Claude Gingras
Stefan Knapp
Susanne Müller
机构
[1] University of Oxford,Structural Genomics Consortium, Nuffield Department of Clinical Medicine
[2] Old Road Campus Research Building,Target Discovery Institute, Nuffield Department of Clinical Medicine
[3] University of Oxford,Lunenfeld
[4] Mount Sinai Hospital,Tanenbaum Research Institute
[5] University of Toronto,Department of Molecular Genetics
[6] University of Oxford,Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences
[7] Cardiff University,Nanotether Discovery Sciences Ltd, Museum Avenue
来源
Epigenetics & Chromatin | / 7卷
关键词
Bromodomain; Cell-based assay; Confocal microscopy; Epigenetics; Fluorescence recovery after photobleaching; Histone acetylation; Small-molecule inhibitor;
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