Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: A case report

被引：11

作者：

Smith J.C. ^{[1
]}

Cohen E. ^{[1
]}

机构：

[1] Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto

来源：

Journal of Medical Case Reports | / 3卷 / 1期

关键词：

Pleural Effusion; Pleural Fluid; Ventriculoperitoneal Shunt; Shunt Insertion; Shunt Series;

D O I：

10.1186/1752-1947-3-6495

中图分类号：

学科分类号：

摘要：

Introduction. Pleural effusion secondary to ventriculoperitoneal shunt insertion is a rare and potentially life-threatening occurrence. Case presentation. We describe a 14-month-old Caucasian boy who had a ventriculoperitoneal shunt inserted for progressive hydrocephalus of unknown etiology. Two and a half months post-shunt insertion, the patient presented with mild respiratory distress. A chest radiograph revealed a large right pleural effusion and a shunt series demonstrated an appropriately placed distal catheter tip. A subsequent abdominal ultrasound revealed marked ascites. Fluid drained via tube thoracostomy was sent for beta-2-transferrin electrophoresis. A positive test was highly suggestive of cerebral spinal fluid hydrothorax. Post-externalization of the ventriculoperitoneal shunt, the ascites and pleural effusion resolved. Conclusion. Testing for beta-2-transferrin protein in pleural fluid may serve as a useful technique for diagnosing cerebrospinal fluid hydrothorax in patients with ventriculoperitoneal shunts. © 2009 Smith and Cohen; licensee Cases Network Ltd.

引用

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