WAY-100635 is a potent dopamine D4 receptor agonist

被引：0
作者：
Benjamin R. Chemel
Bryan L. Roth
Blaine Armbruster
Val J. Watts
David E. Nichols
机构：
[1] Purdue University,Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences
[2] Psychiatry,Departments of Biochemistry
[3] Neurosciences and NIMH Psychoactive Drug Screening Program,undefined
[4] Case Western Reserve University Medical School,undefined
来源：
Psychopharmacology | 2006年 / 188卷
关键词：
WAY-100635; WAY-100634; 5-HT; D; D; Receptor selectivity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：244 / 251
页数：7
相关论文
共 45 条
  • [21] Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-11C]WAY-100635 -: considerations on the validity of cerebellum as a reference region
    Hirvonen, Jussi
    Kajander, Jaana
    Allonen, Topias
    Oikonen, Vesa
    Nagren, Kjell
    Hietala, Jarmo
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2007, 27 (01) : 185 - 195
  • [22] Two C-Methyl Derivatives of [11C]WAY-100635 – Effects of an Amido α-Methyl Group on Metabolism and Brain 5-HT1A Receptor Radioligand Behavior in Monkey*
    Julie A. McCarron
    Sandrine Marchais-Oberwinkler
    Victor W. Pike
    Jari Tarkiainen
    Christer Halldin
    Judit Sóvagó
    Balàzs Gulyas
    Hakan V. Wikström
    Lars Farde
    Molecular Imaging and Biology, 2005, 7 : 209 - 219
  • [23] Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties
    Assie, MB
    Koek, W
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1996, 304 (1-3) : 15 - 21
  • [24] Two C-methyl derivatives of [11C]WAY-100635 -: Effects of an amido α-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey
    McCarron, JA
    Marchais-Oberwinkler, S
    Pike, VW
    Tarkiainen, J
    Halldin, C
    Sóvagó, J
    Gulyas, BZ
    Wikström, HV
    Farde, L
    MOLECULAR IMAGING AND BIOLOGY, 2005, 7 (03) : 209 - 219
  • [25] The effects of A 5-HT1A receptor agonist and antagonist on the 5-hydroxytryptamine release in the central nucleus of the amygdala: a microdialysis study with flesinoxan and WAY 100635
    Fokko Bosker
    Dorien Vrinten
    André Klompmakers
    H. Westenberg
    Naunyn-Schmiedeberg's Archives of Pharmacology, 1997, 355 : 347 - 353
  • [26] Quantification of the radio-metabolites of the serotonin-1A receptor radioligand [carbonyl-11C]WAY-100635 in human plasma: An HPLC-assay which enables measurement of two patients in parallel
    Nics, L.
    Hahn, A.
    Zeilinger, M.
    Vraka, C.
    Ungersboeck, J.
    Haeusler, D.
    Hartmann, S.
    Wagner, K-H.
    Lanzenberger, R.
    Wadsak, W.
    Mitterhauser, M.
    APPLIED RADIATION AND ISOTOPES, 2012, 70 (12) : 2730 - 2736
  • [27] Perinatal Treatments with the Dopamine D2-Receptor Agonist Quinpirole Produces Permanent D2-Receptor Supersensitization: a Model of Schizophrenia
    Richard M. Kostrzewa
    Przemysław Nowak
    Ryszard Brus
    Russell W. Brown
    Neurochemical Research, 2016, 41 : 183 - 192
  • [28] The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy
    P. J. Cocker
    M. Y. Lin
    M. M. Barrus
    B. Le Foll
    C. A. Winstanley
    Psychopharmacology, 2016, 233 : 3135 - 3147
  • [29] Role of Dopamine D4 Receptors in Motor Hyperactivity Induced by Neonatal 6-Hydroxydopamine Lesions in Rats
    Kehong Zhang
    Frank I Tarazi
    Ross J Baldessarini
    Neuropsychopharmacology, 2001, 25 : 624 - 632
  • [30] The antipsychotic potential of l-stepholidine—a naturally occurring dopamine receptor D1 agonist and D2 antagonist
    Sridhar Natesan
    Greg E. Reckless
    Karen B. L. Barlow
    John Odontiadis
    José N. Nobrega
    Glen B. Baker
    Susan R. George
    David Mamo
    Shitij Kapur
    Psychopharmacology, 2008, 199 : 275 - 289
12345