Gender differences in lipoprotein metabolism and dietary response: Basis in hormonal differences and implications for cardiovascular disease

被引：116

作者：

Knopp R.H. ^{[1
]}

Paramsothy P. ^{[1
]}

Retzlaff B.M. ^{[1
]}

Fish B. ^{[1
]}

Walden C. ^{[1
]}

Dowdy A. ^{[1
]}

Tsunehara C. ^{[1
]}

Aikawa K. ^{[1
]}

Cheung M.C. ^{[1
]}

机构：

[1] Northwest Lipid Research Clinic, University of Washington, Seattle, WA 98104

来源：

Current Atherosclerosis Reports | 2005年 / 7卷 / 6期

关键词：

Cholesterol; Lipoprotein Metabolism; Arterioscler Thromb Vasc Biol; Hepatic Lipase Activity; Dietary Response;

D O I：

10.1007/s11883-005-0065-6

中图分类号：

学科分类号：

摘要：

The transport of fat in the blood stream is approximately twice as fast in women as men. Disease states such as obesity and diabetes are associated with greater lipoprotein abnormalities in women compared with men. A greater increment in cardiovascular disease risk in women is linked to these abnormalities. A greater change in triglyceride level and a lesser change in low-density lipoprotein are observed in women than men with high-carbohydrate or high-fat feeding. Most consistent are greater changes in high-density lipoprotein (HDL), HDL2, and apolipoprotein A-I levels in women compared with men with high-carbohydrate or high-fat feeding. Dietary fat restriction in women appears to have a less beneficial lipoprotein effect than in men. Dietary fat restriction for heart disease prevention may be less ideal in women than in men. Copyright © 2005 by Current Science Inc.

引用

页码：472 / 479

页数：7

共 46 条

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