Synthesis and Spectroscopic Studies of Phenanthroimidazole-Imine Derivatives and Evaluation of Their Antioxidant Activity

被引:0
作者
Sibel Gülle
Seçil Çelik Erbaş
Ataç Uzel
机构
[1] Manisa Celal Bayar University,Faculty of Arts and Science, Department of Chemistry
[2] Manisa Celal Bayar University,Faculty of Engineering, Department of Metallurgy and Materials Engineering
[3] Ege University,Faculty of Science, Department of Biology
来源
Journal of Fluorescence | 2018年 / 28卷
关键词
Phenanthroimidazole; Antioxidant activity; DPPH; Absorption and emission spectroscopy; Fluorescence;
D O I
暂无
中图分类号
学科分类号
摘要
The phenanthroimidazole derivatives are used in the drug industry in large scale. In this study four new phenanthroimidazole-imine derivatives were synthesized and their spectroscopic studies as well as their antioxidant behaviors were examined. Structural analyses were made by FT-IR, 1H-NMR, 13C-NMR, LC-MS spectroscopy techniques. UV–vis absorption and emission spectroscopy techniques have been used to determine the photophysical characteristics of four newly synthesized phenanthroimidazoles. The maximum absorption and emission wavelengths, molar extinction coefficients (ε), singlet energy levels (Es), Stokes’ shift values (Δλ) of phenanthroimidazole-imine derivatives are given. Additionally, the antioxidant behavior of all compounds were investigated which the ascorbic acid used as standard molecule in present study.
引用
收藏
页码:217 / 223
页数:6
相关论文
共 95 条
[1]  
Gülçin İ(2012)Antioxidant activity of food constituents: an overview Arch Toxicol 86 345-391
[2]  
Youssef KM(2004)Synthesis of curcumin analogues as potential antioxidant cancer chemopreventive agents Arch Pharm Med Chem 337 42-54
[3]  
El-Sherbeny MA(2009)Antioxidant properties of an endogenous thiol: alpha-lipoic acid, useful in the prevention of cardiovascular diseases J Cardiovasc Pharmacol 54 391-398
[4]  
El-Shafie FS(2009)Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options Curr Neuropharmacol 7 65-74
[5]  
Farag HA(2012)Antioxidant therapies for Alzheimer’s disease Oxid Med Cell Longev 3 461-491
[6]  
Al-Deeb OA(2013)The role of oxidative stress in Parkinson’s disease J Parkinsons Dis 45 1820-1827
[7]  
Awadalla SA(2000)Experimental ulcerative colitis impairs antioxidant defense system in rat intestine Dig Dis Sci 58 85-90
[8]  
Ghibu S(2010)Role of antioxidants in the skin: anti-aging effects J Dermatol Sci 16 33-50
[9]  
Richard C(1997)Antioxidants in human health and disease Ann Rev Nutr 20 933-956
[10]  
Vergely C(1996)Structure-antioxidant activity relationships of flavonoids and phenolic acids Free Radic Biol Med 14 45-50