Prostate cancer–Exercise and Metformin Trial (Pre-EMpT): study protocol for a feasibility factorial randomized controlled trial in men with localised or locally advanced prostate cancer

被引：0
作者：
Lucy McGeagh
Luke A. Robles
Raj Persad
Edward Rowe
Amit Bahl
Jonathan Aning
Anthony Koupparis
Paul Abrams
Claire Perks
Jeffrey Holly
Lyndsey Johnson
Constance Shiridzinomwa
Amarnath Challapalli
Ellie Shingler
Hilary Taylor
Jon Oxley
Meda Sandu
Richard M. Martin
J. Athene Lane
机构：
[1] NIHR Bristol Biomedical Research Centre,Bristol Haematology and Oncology Centre
[2] University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol,undefined
[3] Supportive Cancer Care Research Group,undefined
[4] Faculty of Health and Life Sciences,undefined
[5] Oxford Institute of Nursing,undefined
[6] Midwifery and Allied Health Research,undefined
[7] Oxford Brookes University,undefined
[8] Bristol Urological Institute,undefined
[9] North Bristol NHS Trust,undefined
[10] University Hospitals Bristol and Weston NHS Foundation Trust,undefined
[11] Insulin-like Growth Factors and Metabolic Endocrinology Group,undefined
[12] Translational Health Sciences,undefined
[13] Bristol Medical School,undefined
[14] University of Bristol,undefined
[15] Clinical Research Centre,undefined
[16] North Bristol NHS Trust,undefined
[17] Bristol Medical School,undefined
[18] Population Health Sciences,undefined
[19] University of Bristol,undefined
[20] Department of Cellular Pathology,undefined
[21] North Bristol NHS Trust,undefined
来源：
Pilot and Feasibility Studies | / 8卷
关键词：
Prostate cancer; Metformin; Physical activity; Feasibility randomised controlled trial; Localised; Locally advanced; Radiotherapy; Prostatectomy; Active surveillance;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 155 条
[1]  
Albertsen PC(2005)20-year outcomes following conservative management of clinically localized prostate cancer JAMA. 293 2095-2101
[2]  
Hanley JA(2004)Natural history of early, localized prostate cancer Jama. 291 2713-2719
[3]  
Fine J(2016)Patient-reported outcomes after monitoring, surgery, or radiotherapy for prostate cancer N Engl J Med 375 1425-1437
[4]  
Johansson JE(2004)Biochemical relapse after primary treatment for prostate cancer: studies on natural history and therapeutic considerations J Natl Compr Cancer Netw 2 249-256
[5]  
Andrén O(2008)Physical activity in relation to total, advanced, and fatal prostate cancer Cancer Epidemiol Biomark Prev 17 2458-2466
[6]  
Andersson SO(2011)Physical activity and survival after prostate cancer diagnosis in the health professionals follow-up study J Clin Oncol. 29 726-32
[7]  
Dickman PW(2017)The feasibility of the Prostate cancer: Evidence of Exercise and Nutrition Trial (PrEvENT) dietary and physical activity modifications: a qualitative study Trials. 18 106-206
[8]  
Holmberg L(2003)A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro Prostate 56 201-s866
[9]  
Magnuson A(2007)Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence Am J Clin Nutr 86 s858-1353
[10]  
Donovan JL(2008)Prostate inflammation and its potential impact on prostate cancer: a current review J Cell Biochem 103 1344-37
12345678910