Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

被引:0
作者
Hoang T. Nguyen
Julien Bryois
April Kim
Amanda Dobbyn
Laura M. Huckins
Ana B. Munoz-Manchado
Douglas M. Ruderfer
Giulio Genovese
Menachem Fromer
Xinyi Xu
Dalila Pinto
Sten Linnarsson
Matthijs Verhage
August B. Smit
Jens Hjerling-Leffler
Joseph D. Buxbaum
Christina Hultman
Pamela Sklar
Shaun M. Purcell
Kasper Lage
Xin He
Patrick F. Sullivan
Eli A. Stahl
机构
[1] Icahn School of Medicine at Mount Sinai,Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology
[2] Karolinska Institutet,Department of Medical Epidemiology and Biostatistics
[3] Broad Institute of MIT and Harvard,Stanley Center for Psychiatric Research
[4] Massachusetts General Hospital,Department of Surgery
[5] Icahn School of Medicine at Mount Sinai,Charles Bronfman Institute for Personalized Medicine
[6] Karolinska Institutet,Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics
[7] Vanderbilt University Medical Center,Division of Genetic Medicine, Departments of Medicine, Psychiatry and Biomedical Informatics, Vanderbilt Genetics Institute
[8] Harvard Medical School,Department of Genetics
[9] Verily Life Sciences,Seaver Autism Center, Department of Psychiatry
[10] Icahn School of Medicine at Mount Sinai,The Mindich Child Health and Development Institute
[11] Icahn School of Medicine at Mount Sinai,Friedman Brain Institute
[12] Icahn School of Medicine at Mount Sinai,Department of Functional Genomics, The Center for Neurogenomics and Cognitive Research
[13] VU University and VU Medical Center,Department of Molecular and Cellular Neurobiology, The Center for Neurogenomics and Cognitive Research
[14] VU University,Sleep Center, Brigham and Women’s Hospital
[15] Harvard Medical School,Department of Human Genetics
[16] University of Chicago,Departments of Genetics and Psychiatry
[17] University of North Carolina,undefined
来源
Genome Medicine | / 9卷
关键词
De novo mutations; Rare variants; Schizophrenia; Autism; Developmental disorders; Intellectual disability; Epilepsy; Hierarchical model;
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