Kinetic chemiluminescence as a method for study of free radical reactions

被引：16
作者：
Vladimirov Y.A. [1 ]
Proskurnina E.V. [1 ]
Izmajlov D.Y. [1 ]
机构：
[1] Faculty of Fundamental Medicine, Moscow State University
来源：
Biophysics | 2011年 / 56卷 / 6期
关键词：
activators of chemiluminescence; chemiluminescence; free radicals; lipid peroxidation;
D O I：
10.1134/S0006350911060200
中图分类号：
学科分类号：
摘要：
The review gives concepts of analysis of kinetics of complex reactions with the participation of free radicals. The concepts are based on the comparison of kinetic curves of chemiluminescent reactions in the presence of a physical enhancer coumarin C-525 with the simulated kinetic functions. This method was applied to the investigation of the mechanism of a branched-chain reaction of lipid peroxidation in biological and phospholipid membranes as well as to the effect of antioxidants and determination of their activities. It was also used for studying the reaction of formation of free radicals in the complex of cytochrome c with cardiolipin. This reaction plays a key role in the initiation of apoptosis. © 2011 Pleiades Publishing, Ltd.
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页码：1055 / 1062
页数：7
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