Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p

被引:0
作者
Ying Gao
Zheng Yin
Yunling Qi
Hong Peng
Wenbin Ma
Ruizhi Wang
Wen Li
机构
[1] Sun Yat-sen University,Laboratory of General Surgery, The First Affiliated Hospital
[2] Sun Yat-sen University,Division of Vascular Surgery, National Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital
[3] Sun Yat-sen University,Center of hepato
[4] Sun Yat-sen University,pancreatobiliary surgery, The First Affiliated Hospital
[5] Sun Yat-sen University,School of Life Sciences
来源
Cancer Cell International | / 22卷
关键词
GOLPH3; Hepatocellular carcinoma; Exosomal miR-494-3p; Angiogenesis; Sorafenib resistance;
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[1]  
Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[2]  
Ferlay J(2010)Hepatocellular carcinoma: a global view Nat Rev Gastroenterol Hepatol 7 448-458
[3]  
Soerjomataram I(2018)Hepatocellular carcinoma Lancet 391 1301-1314
[4]  
Siegel RL(2015)Systemic treatment of advanced hepatocellular carcinoma: from disillusions to new horizons Eur J Cancer 51 327-339
[5]  
Torre LA(2008)Sorafenib in advanced hepatocellular carcinoma N Engl J Med 359 378-390
[6]  
Jemal A(2016)Hepatocellular carcinoma Nat Rev Dis Prim 2 16018-2234
[7]  
Yang JD(2010)Signaling from the Golgi: mechanisms and models for Golgi phosphoprotein 3-mediated oncogenesis Clin Cancer Res 16 2229-1090
[8]  
Roberts LR(2009)GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer Nature 459 1085-1823
[9]  
Forner A(2018)Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway BMC Cancer 18 661-501
[10]  
Reig M(2020)Oncogenic roles of GOLPH3 in the physiopathology of cancer Int J Mol Sci 15 1812-4790