Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

[1] Kozak M(1989)The scanning model for translation: an update J Cell Biol 108 229-241

[2] Kozak M(2002)Pushing the limits of the scanning mechanism for initiation of translation Gene 299 1-34

[3] Kwon H-S(2001)Posttranscriptional regulation of human ADH5/FDH and Myf6 gene expression by upstream AUG codons Arch Biochem Biophys 386 163-171

[4] Lee D-K(2001)Inhibition of corticotropin releasing hormone type-1 receptor translation by an upstream AUG triplet in the 5' untranslated region Mol Pharmacol 59 485-492

[5] Lee J-J(2003)The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties J Biol Chem 278 25716-25721

[6] Edenberg HJ(2001)Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5' untranslated regions J Biol Chem 276 1311-1316

[7] Ahn Y-H(2004)5'-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation Nucleic Acids Res 32 1382-1391

[8] Hur M-W(2005)Translation of the first upstream ORF in the hepatitis B virus pregenomic RNA modulates translation at the core and polymerase initiation codons Nucleic Acids Res 33 1169-1181

[9] Xu G(1997)Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression Nucleic Acids Res 25 1678-1684

[10] Rabadan-Diehl C(1998)Cloning and characterization of promoter and 5'-UTR of the NMDA receptor subunit epsilon 2: evidence for alternative splicing of 5'-non-coding exon Gene 208 259-269

[1] Kozak M(1989)The scanning model for translation: an update J Cell Biol 108 229-241

[2] Kozak M(2002)Pushing the limits of the scanning mechanism for initiation of translation Gene 299 1-34

[3] Kwon H-S(2001)Posttranscriptional regulation of human ADH5/FDH and Myf6 gene expression by upstream AUG codons Arch Biochem Biophys 386 163-171

[4] Lee D-K(2001)Inhibition of corticotropin releasing hormone type-1 receptor translation by an upstream AUG triplet in the 5' untranslated region Mol Pharmacol 59 485-492

[5] Lee J-J(2003)The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties J Biol Chem 278 25716-25721

[6] Edenberg HJ(2001)Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5' untranslated regions J Biol Chem 276 1311-1316

[7] Ahn Y-H(2004)5'-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation Nucleic Acids Res 32 1382-1391

[8] Hur M-W(2005)Translation of the first upstream ORF in the hepatitis B virus pregenomic RNA modulates translation at the core and polymerase initiation codons Nucleic Acids Res 33 1169-1181

[9] Xu G(1997)Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression Nucleic Acids Res 25 1678-1684

[10] Rabadan-Diehl C(1998)Cloning and characterization of promoter and 5'-UTR of the NMDA receptor subunit epsilon 2: evidence for alternative splicing of 5'-non-coding exon Gene 208 259-269