Peptide-Based and Polypeptide-Based Gene Delivery Systems

被引:0
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作者
Jie Chen
Xiuwen Guan
Yingying Hu
Huayu Tian
Xuesi Chen
机构
[1] Chinese Academy of Sciences,Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry
[2] University of Chinese Academy of Sciences,undefined
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关键词
Gene delivery; Polypeptide; Polymeric carriers; Genetic disorders; Multifunctional; Gene vaccine;
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摘要
Peptide-based and polypeptide-based gene carriers are emerging as the most potentially useful agents in the field of gene therapy. Here we summarize the methods used for the preparation of peptides and polypeptides, address the primary types of peptide-based gene delivery systems, demonstrate their applications in gene therapy, and attempt to propose possible future directions in the development of peptide-based and polypeptide-based gene carriers for specific applications.
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