Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics

被引：0
|
作者：
Andrea M. Bradford
Kevin M. Savage
Declan N. C. Jones
Mikhail Kalinichev
机构：
[1] GlaxoSmithKline plc,Biology Department, Neurosciences Centre of Excellence for Drug Discovery
[2] GlaxoSmithKline plc,Research and Development Information Technology
[3] GlaxoSmithKline plc,European Centre of Excellence for External Drug Discovery
[4] Immeuble Alliance,CNS Business Unit, Addex Pharmaceuticals, Bâtiment A&C
来源：
Psychopharmacology | 2010年 / 212卷
关键词：
Glutamate; MK-801; Schizophrenia; Locomotor activity; Hyperactivity; Antipsychotic;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：155 / 170
页数：15
相关论文
共 11 条
  • [1] Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics
    Bradford, Andrea M.
    Savage, Kevin M.
    Jones, Declan N. C.
    Kalinichev, Mikhail
    PSYCHOPHARMACOLOGY, 2010, 212 (02) : 155 - 170
  • [2] Effect of antipsychotics on spontaneous hyperactivity and hypersensitivity to MK-801-induced hyperactivity in rats prenatally exposed to methylazoxymethanol
    Le Pen, Gwenaeelle
    Jay, Therese M.
    Krebs, Marie-Odile
    JOURNAL OF PSYCHOPHARMACOLOGY, 2011, 25 (06) : 822 - 835
  • [3] The Impact of CB2 Receptor Ligands on the MK-801-Induced Hyperactivity in Mice
    Marta Kruk-Slomka
    Izabela Banaszkiewicz
    Grazyna Biala
    Neurotoxicity Research, 2017, 31 : 410 - 420
  • [4] The Impact of CB2 Receptor Ligands on the MK-801-Induced Hyperactivity in Mice
    Kruk-Slomka, Marta
    Banaszkiewicz, Izabela
    Biala, Grazyna
    NEUROTOXICITY RESEARCH, 2017, 31 (03) : 410 - 420
  • [5] Glycine and D-serine decrease MK-801-induced hyperactivity in mice
    Nilsson, M
    Carlsson, A
    Carlsson, ML
    JOURNAL OF NEURAL TRANSMISSION, 1997, 104 (11-12) : 1195 - 1205
  • [6] Glycine and D-serine decrease MK-801-induced hyperactivity in mice
    M. Nilsson
    A. Carlsson
    M. L. Carlsson
    Journal of Neural Transmission, 1997, 104 : 1195 - 1205
  • [7] Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity
    Hillhouse, Todd M.
    Merritt, Christina R.
    Smith, Douglas A.
    Cajina, Manuel
    Sanchez, Connie
    Porter, Joseph H.
    Pehrson, Alan L.
    FRONTIERS IN PHARMACOLOGY, 2018, 9
  • [8] Clozapine does not require 5-HT1A receptors to block the locomotor hyperactivity induced by MK-801 Clz and MK-801 in KO1A mice
    Cecilia Scorza, Maria
    Castane, Anna
    Bortolozzi, Analia
    Artigas, Francesc
    NEUROPHARMACOLOGY, 2010, 59 (1-2) : 112 - 120
  • [9] Risperidone attenuates MK-801-induced hyperlocomotion in mice via the blockade of serotonin 5-HT2A/2C receptors
    Su, Yun-Ai
    Si, Tian-Mei
    Zhou, Dong-Feng
    Guo, Chun-Mei
    Wang, Xiao-Dong
    Yang, Yang
    Shu, Liang
    Liang, Jian-Hui
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2007, 564 (1-3) : 123 - 130
  • [10] GLP-1 agonist Liraglutide prevents MK-801-induced schizophrenia-like behaviors and BDNF, CREB, p-CREB, Trk-B expressions in the hippocampus and prefrontal cortex in Balb/c mice
    Kutlu, Meltem Donmez
    Kose, Seda
    Akillioglu, Kubra
    BEHAVIOURAL BRAIN RESEARCH, 2023, 445
12