Gastroenteropancreatic neuroendocrine tumors

被引:0
作者
Rayes, Nada [1 ]
Denecke, Timm [2 ]
机构
[1] Univ Klinikum Leipzig, Klin & Poliklin Viszeral Transplantat Thorax & Ge, Liebigstr 20, D-04103 Leipzig, Germany
[2] Univ Klinikum Leipzig, Klin & Poliklin Diagnost & Interventionelle Radio, Leipzig, Germany
来源
RADIOLOGE | 2021年 / 61卷 / 12期
关键词
Neuroendocrine tumors; registries; treatment algorithms; Chromogranin A; Receptors; somatostatin; Peptide receptor radionuclide therapy; ENETS CONSENSUS GUIDELINES; MANAGEMENT; CLASSIFICATION; STANDARDS; UPDATE; CARE;
D O I
10.1007/s00117-021-00929-w
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Neuroendocrine tumors (NET), or more generally neuroendocrine neoplasms (NEN), represent a very heterogeneous group of rare tumors with varying location which are only defined by their endocrine biology and secretion of synaptophysin and chromogranin A. They originate from mesoderm-derived stem cells. In the last few years, the incidence and prevalence of NEN have been steadily increasing. Classification is based on the affected organ, the proliferation rate and presence or absence of hormone production with typical symptoms. Diagnosis and treatment of these tumors is therefore very specific and requires an interdisciplinary approach. Treatment options include endoscopic or surgical resection, drug therapy for control of symptoms and proliferation, locoregional therapy and radionuclide therapy. Guidelines with algorithms for diagnostic workup and treatment are constantly updated.
引用
收藏
页码:1129 / 1138
页数:10
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