Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

被引：0

作者：

Deepak A. Rao

Michael F. Gurish

Jennifer L. Marshall

Kamil Slowikowski

Chamith Y. Fonseka

Yanyan Liu

Laura T. Donlin

Lauren A. Henderson

Kevin Wei

Fumitaka Mizoguchi

Nikola C. Teslovich

Michael E. Weinblatt

Elena M. Massarotti

Jonathan S. Coblyn

Simon M. Helfgott

Yvonne C. Lee

Derrick J. Todd

Vivian P. Bykerk

Susan M. Goodman

Alessandra B. Pernis

Lionel B. Ivashkiv

Elizabeth W. Karlson

Peter A. Nigrovic

Andrew Filer

Christopher D. Buckley

James A. Lederer

Soumya Raychaudhuri

Michael B. Brenner

机构：

[1] Immunology,Division of Rheumatology

[2] and Allergy,Division of Genetics

[3] Brigham and Women’s Hospital and Harvard Medical School,Division of Immunology

[4] Rheumatology Research Group,Division of Rheumatology

[5] Institute of Inflammation and Ageing,Department of Medicine

[6] University of Birmingham,Department of Surgery

[7] Queen Elizabeth Hospital,undefined

[8] Brigham and Women’s Hospital and Harvard Medical School,undefined

[9] Program in Medical and Population Genetics,undefined

[10] Broad Institute of Massachusetts Technical Institute and Harvard University,undefined

[11] Partners Center for Personalized Genetic Medicine,undefined

[12] Bioinformatics and Integrative Genomics,undefined

[13] Harvard University,undefined

[14] Biological and Biomedical Sciences,undefined

[15] Harvard University,undefined

[16] Arthritis and Tissue Degeneration Program,undefined

[17] Hospital for Special Surgery,undefined

[18] David Z. Rosensweig Genomics Research Center,undefined

[19] Hospital for Special Surgery,undefined

[20] Boston Children’s Hospital,undefined

[21] Hospital for Special Surgery,undefined

[22] Weill Cornell Medical College,undefined

[23] Cornell University,undefined

[24] Autoimmunity and Inflammation Program,undefined

[25] Hospital for Special Surgery,undefined

[26] Brigham and Women’s Hospital,undefined

[27] Reumatology Unit,undefined

[28] Karolinska Institutet and Karolinska University Hospital Solna,undefined

[29] Institute of Inflammation and Repair,undefined

[30] University of Manchester,undefined

来源：

Nature | 2017年 / 542卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The authors identify in patients with rheumatoid arthritis a pathogenic subset of CD4+ T cells that augments B cell responses within inflamed tissues.

引用

页码：110 / 114

页数：4

共 37 条

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