1H, 15N, and 13C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei

被引：0
作者：
Xianzhong Xu
Cheryl L. Olson
David M. Engman
James B. Ames
机构：
[1] University of California,Department of Chemistry
[2] Northwestern University,Departments of Pathology and Microbiology–Immunology, Feinberg School of Medicine
来源：
Biomolecular NMR Assignments | 2013年 / 7卷
关键词：
FCaBP; Calcium; EF-hand; Myristoyl switch; NMR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Flagellar calcium binding proteins are expressed in a variety of trypanosomes and are potential drug targets for Chagas disease and African sleeping sickness. We report complete NMR chemical shift assignments of the flagellar calcium binding protein calflagin Tb24 of Trypanosoma brucei. (BMRB no. 18011).
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页码：9 / 12
页数：3
相关论文
共 104 条
  • [1] Buchanan KT(2005)A flagellum-specific calcium sensor J Biol Chem 280 40104-40111
  • [2] Ames JB(2004)The neuronal calcium-sensor proteins Biochim Biophys Acta 1742 59-68
  • [3] Asfaw SH(1995)NMRPipe: a multidimensional spectral processing system based on UNIX pipes J Biomol NMR 6 277-293
  • [4] Wingard JN(1993)Role of the acylated amino terminus of recovering in Ca(2+)-dependent membrane interaction Science 259 829-832
  • [5] Olson CL(2009)Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane J Cell Sci 122 867-874
  • [6] Campana PT(2010)Calflagin inhibition prolongs host survival and suppresses parasitemia in Eukaryot Cell 9 934-942
  • [7] Araujo AP(1989) infection J Biol Chem 264 18627-18631
  • [8] Engman DM(1999)A novel flagellar Ca2+ -binding protein in trypanosomes EMBO J 18 2057-2065
  • [9] Burgoyne RD(1992)Flagellar protein localization mediated by a calcium-myristoyl/palmitoyl switch mechanism Mol Biochem Parasitol 51 99-110
  • [10] Delaglio F(1996)Purification of novel calcium binding proteins from Trends Biochem Sci 21 14-17
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