The Emerging Roles of E3 Ligases and DUBs in Neurodegenerative Diseases

被引：0
作者：
Na Liu
Miao-Miao Lin
Yan Wang
机构：
[1] Soochow University,Department of Pharmacology College of Pharmaceutical Sciences, Suzhou Key Laboratory of Aging and Nervous Diseases, and Jiangsu Key Laboratory of Neuropsychiatric Diseases
来源：
Molecular Neurobiology | 2023年 / 60卷
关键词：
Neurodegenerative diseases; Ubiquitination; E3 ubiquitin ligases; Deubiquitinating enzymes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Despite annual increases in the incidence and prevalence of neurodegenerative diseases, there is a lack of effective treatment strategies. An increasing number of E3 ubiquitin ligases (E3s) and deubiquitinating enzymes (DUBs) have been observed to participate in the pathogenesis mechanisms of neurodegenerative diseases, on the basis of which we conducted a systematic literature review of the studies. This review will help to explore promising therapeutic targets from highly dynamic ubiquitination modification processes.
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页码：247 / 263
页数：16
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