Premature aging of leukocyte DNA methylation is associated with type 2 diabetes prevalence

被引:0
作者
Gidon Toperoff
Jeremy D Kark
Dvir Aran
Hisham Nassar
Wiessam Abu Ahmad
Ronit Sinnreich
Dima Azaiza
Benjamin Glaser
Asaf Hellman
机构
[1] Hebrew University-Hadassah Medical School,Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel
[2] Hebrew University and Hadassah Medical Organization,Canada
[3] Hadassah-Hebrew University Medical Center,Epidemiology Unit, Braun School of Public Health and Community Medicine
[4] Hadassah Medical Organization,Cardiology Department
[5] St Joseph Hospital (East Jerusalem),School of Computer Science and Engineering
[6] Hebrew University,Endocrinology and Metabolism Service, Department of Internal Medicine
[7] Hadassah-Hebrew University Medical Center,undefined
[8] Hadassah Medical Organization,undefined
来源
Clinical Epigenetics | 2015年 / 7卷
关键词
Type 2 diabetes; DNA methylation; Epigenetic aging; Leukocytes; East Jerusalem Palestinians; Ashkenazi Jews; Population epigenetics; Ethnic groups;
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[1]  
Alhyas L(2012)Prevalence of type 2 diabetes in the states of the co-operation council for the Arab States of the Gulf: a systematic review PLoS One 7 e40948-42
[2]  
McKay A(1998)High prevalence of diabetes in Bahrainis. Associations with ethnicity and raised plasma cholesterol Diabetes Care 21 936-602
[3]  
Majeed A(1997)Prevalence of glucose intolerance in urban and rural communities in Saudi Arabia Diabet Med 14 595-40
[4]  
Al-Mahroos F(2012)Type II diabetes mellitus in Arabic-speaking countries Int J Endocrinol 2012 902873-54
[5]  
McKeigue PM(2011)National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants Lancet 378 31-45
[6]  
Al-Nuaim AR(2012)Adult-onset diabetes among Arabs and Jews in Israel: a population-based study Diabet Med 29 748-26
[7]  
Badran M(2014)Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets Cell Metab 19 135-12
[8]  
Laher I(2012)DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients EMBO J 31 1405-83
[9]  
Danaei G(2012)Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes Mol Endocrinol 26 1203-21
[10]  
Finucane MM(2012)Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes PLoS One 7 e51302-89