共 106 条
[1]
Bodell W.J.(1986)Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea Carcinogenesis 7 879-883
[2]
Aida T.(1981)Pharmacology of cyclophosphamide and metabolites Cancer Treat Rep 65 89-95
[3]
Berger M.S.(2003)Variability and regulation of O6-alkylguanine-DNA alkyltransferase Carcinogenesis 24 625-635
[4]
Rosenblum M.L.(2000)Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents N Engl J Med 343 1350-1354
[5]
Colvin M.(1992)Detection of messenger RNA from O6-methylguanine-DNA methyltransferase gene MGMT in human normal and tumor tissues J Natl Cancer Inst 84 337-340
[6]
Hilton J.(1990)Expression of the O6-methylguanine-DNA methyltransferase gene MGMT in MER+ and MER-human tumor cells Cancer Res 50 7908-7911
[7]
Margison G.P.(1994)Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells J Biol Chem 269 17228-17237
[8]
Povey A.C.(1999)Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia Cancer Res 59 793-797
[9]
Kaina B.(1998)O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics Cancer Res 58 1068-1073
[10]
Santibanez Koref M.F.(2004)Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide Clin Cancer Res 10 1871-1874