Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model

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作者
Hanako Ono
Yasuhito Arai
Eisaku Furukawa
Daichi Narushima
Tetsuya Matsuura
Hiromi Nakamura
Daisuke Shiokawa
Momoko Nagai
Toshio Imai
Koshi Mimori
Koji Okamoto
Yoshitaka Hippo
Tatsuhiro Shibata
Mamoru Kato
机构
[1] National Cancer Center Research Institute,Division of Bioinformatics
[2] National Cancer Center Research Institute,Division of Cancer Genomics
[3] National Cancer Center Research Institute,Department of Animal Experimentation
[4] National Cancer Center Research Institute,Division of Cancer Differentiation
[5] Department of Surgery,Division of Biochemistry and Molecular Carcinogenesis
[6] Kyushu University Beppu Hospital,Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science
[7] Chiba Cancer Center Research Institute,undefined
[8] The University of Tokyo,undefined
来源
BMC Biology | / 19卷
关键词
Single-cell sequencing; Cancer genomics; Colorectal cancer; Tumorigenesis; Intra-tumor heterogeneity;
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