Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer

[1] Jemal A(2010)Cancer statistics CA Cancer J Clin 60 277-300

[2] Siegel R(2004)Pancreatic cancer Lancet 363 1049-1057

[3] Xu J(2005)Treatment for pancreatic cancer: current therapy and continued progress Gastroenterology 128 1642-1654

[4] Ward E(2007)Molecular pathogenesis of pancreatic cancer: advances and challenges Curr Mol Med 7 504-521

[5] Li D(2006)Anticancer activities of histone deacetylase inhibitors NATURE REVIEWS 5 769-784

[6] Xie K(2007)Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine Biochim Biophys Acta 1773 1095-1106

[7] Wolff R(2006)Histone deacetylase inhibitors: a novel target of anticancer therapy (review) Oncol Rep 15 489-494

[8] Abbruzzese JL(2007)The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo J Transl Med 5 49-283

[9] Lockhart AC(2007)The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo Cancer Chemother Pharmacol 60 275-2059

[10] Rothenberg ML(2011)Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors J Clin Oncol 29 2052-176

[1] Jemal A(2010)Cancer statistics CA Cancer J Clin 60 277-300

[2] Siegel R(2004)Pancreatic cancer Lancet 363 1049-1057

[3] Xu J(2005)Treatment for pancreatic cancer: current therapy and continued progress Gastroenterology 128 1642-1654

[4] Ward E(2007)Molecular pathogenesis of pancreatic cancer: advances and challenges Curr Mol Med 7 504-521

[5] Li D(2006)Anticancer activities of histone deacetylase inhibitors NATURE REVIEWS 5 769-784

[6] Xie K(2007)Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine Biochim Biophys Acta 1773 1095-1106

[7] Wolff R(2006)Histone deacetylase inhibitors: a novel target of anticancer therapy (review) Oncol Rep 15 489-494

[8] Abbruzzese JL(2007)The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo J Transl Med 5 49-283

[9] Lockhart AC(2007)The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo Cancer Chemother Pharmacol 60 275-2059

[10] Rothenberg ML(2011)Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors J Clin Oncol 29 2052-176